Dengue virus (DENV) is a mosquito-transmitted RNA virus that infects an estimated 390 million humans each year. Here, we review recent advances in our understanding of the biology of DENV and describe knowledge gaps that have impacted the development of effective vaccines and therapeutics.

In South America, the epidemiology and ecology of dengue fever are strongly associated with human habits because the vector Aedes aegypti is strictly urban. Thus, the evaluation of people's knowledge and practice (PKP) is of great importance to improve integrated control measures. A PKP evaluation has been done in a suburb of Brasilia. Thirty questions were submitted to 130 habitants about inco...

A checklist of the mosquito fauna encountered during arboviral studies in Iquitos, Peru, is presented. A total of 16 genera, 30 subgenera, and 96 species were identified, including 24 species reported from Peru for the 1st time. Notations on the taxonomy and biology for 28 species are also provided.

t has been shown that stress can induce hyperglycemia in several animal models of type II diabetes (1). Cori theorized a link between the physiologic stress response and development of hyperglycemia. In his experiments with rabbits, Cori demonstrated that continuous infusion of epinephrine exacerbated hyperglycemia (2). Van Loon continued these researches by infusing beta endorphins intracister...

Free or subsidised mosquito net (MN) distribution has been an increasingly important tool in efforts to combat malaria in recent decades throughout the developing world, making great strides towards eradicating this hugely detrimental disease. However, there has been increasing concern in the natural resource management and healthcare communities over alternative use of MNs, particularly in art...

background: wolbachia  are common intracellular bacteria that infect different groups of arthropods including mos­quitoes. these bacteria modify host biology and may induce feminization, parthenogenesis, male killing and cyto­plasmic incompatibility (ci). recently wolbachia  is being nominated as a bio-agent and paratransgenic candidate to control mosquito borne diseases. methods: here we repor...

Malaria epidemiology is complex due to multiplicity of disease vectors, sibling species complex and variations in bionomical characteristics, vast varied terrain, various ecological determinants. There are six major mosquito vector taxa in India, viz. Anopheles culicifacies, An. fluviatilis, An. stephensi, An. minimus, An. dirus and An. sundaicus. Among these, An. culicifacies is widely distrib...

Mosquito larvae use a digestive strategy that is relatively rare in nature. The anterior half of the larval mosquito midgut has a luminal pH that ranges between 10.5 and 11.5. Most other organisms, both large and small, initiate digestion in an acid medium. The relative uniqueness of the highly alkaline digestive strategy has been a long-standing research focus in larval lepidopterans. More rec...