Giant and stable worm micelles formed from poly(ethylene glycol) (PEG)-based diblock copolymer amphiphiles have the potential advantage compared to smaller assemblies for delivery of a large quantity of hydrophobic drugs or dyes per carrier. Here we show that worm micelles can be targeted to cells with internalization and delivery of nontoxic dyes as well as cytotoxic drugs. Constituent copolym...

In 1963 Sydney Brenner proposed to study the development of multi-cellular organisms using a genetic approach in a simple animal. He settled on a small, transparent nematode, Caenorhabditis elegans, which develops quickly and is anatomically simple with less than a thousand somatic cells. Almost half a century later there are many more researchers studying C. elegans than there are somatic cell...

Benzyl methacrylate (BzMA) is polymerized using a poly(lauryl methacrylate) macromolecular chain transfer agent (PLMA macro-CTA) using reversible addition-fragmentation chain transfer (RAFT) polymerization at 70 °C in n-dodecane. This choice of solvent leads to an efficient dispersion polymerization, with polymerization-induced self-assembly (PISA) occurring via the growing PBzMA block to produ...

SUMMARY hydatic cyst is a serious disease of man. That cause by a worm called taenia echinocococus, the adult worm lives in small bowel of dog and other canine host. The dog is the usual definitive host of this parasite and is important for transmition of this disease. In this study a total of 283 stray dags Teheran country were investigated for the present of intestinal metazoan parasites. T...