Voltage-dependent gating mechanisms of large conductance Ca(2+) and voltage-activated (BK) channels were investigated using two-dimensional maximum likelihood analysis of single-channel open and closed intervals. To obtain sufficient data at negative as well as positive voltages, single-channel currents were recorded at saturating Ca(2+) from BK channels mutated to remove the RCK1 Ca(2+) and Mg...

We compared growth kinetics of Prorocentrum donghaiense cultures on different nitrogen (N) compounds including nitrate (NO3 ), ammonium (NH4 ), urea, glutamic acid (glu), dialanine (diala) and cyanate. P. donghaiense exhibited standard Monod-type growth kinetics over a range of N concentraions (0.5–500 mmol N L for NO3 2 and NH4 , 0.5–50 mmol N L for urea, 0.5–100 mmol N L for glu and cyanate, ...

The global asymptotic behavior of solutions of the variable yield model is determined. The model generalizes the classical Monod model and it assumes that the yield is an increasing function of the nutrient concentration. In contrast to the Monod model, it is demonstrated that the variable yield model exhibits sustained oscillations. Moreover, it is shown that the variable yield model may under...

Underground Hydrogen storage (UHS) is a promising technology for safe of large quantities hydrogen, in daily to seasonal cycles depending on the consumption requirements. The development UHS requires anticipating hydrogen behavior prevent any unexpected economic or environmental impact. An open question reactivity underground porous media storages. Indeed, there no consensus effects lack geoche...

Jacques Monod and Francois Jacob, our heroes, described a gene-regulatory world run exclusively by repressors. The activities of repressors, their abilities to bind DNA as we later learned, would be controlled — helped or hindered — by small molecules that bind these proteins. They showed [1] that networks of considerable complexity could be created with such a regulatory system. There was no n...

Some of these studies have been reported in a preliminary communication, Hoffee, P., and E. Englesberg, Bacteriol. Proc., 1962, p. 120. Abbreviations: ATP, adenosine triphosphate; aMG, alpha methyl D-glucopyranoside. t Predoctoral Research Fellow, U.S. Public Health Service. l Rickenberg, H. V., G. N. Cohen, G. Buttin, and J. Monod, Ann. Inst. Pasteur, 91, 829 (1956). 2 Cohen, G. N., and J. Mon...