Historically, chemistry educators have tried to render chemical structures and processes more visible through the use of vivid, albeit excessively simple, visual metaphors such as the solar system serving as a model of the structure of an atom. While marginally useful in early stages of learning, such metaphors eventually interfere with students obtaining a deeper understanding of chemical conc...

요 약 최근 생체 분자를 이용한 정보 처리 기술의 발전은 분자 수준에서의 생화학적 정보 처리의 가능성을 제시하였으며 더 나아가 유전자 분석이나 질병진단과 같은 의료 목적의 응용 개발을 목표로 하고 있다. 이러한 분자 정보 처리 기술은 기존의 실리콘 컴퓨터 기반의 방법론과는 달리 생화학적 정보를 전기적 신호로의 변환 과정 없이 시험관 내에서 직접 처리하며 결과적으로 정보 손실을 최소화하며 최종 결과를 얻기까지의 절차를 단축시킨다. 그러나 현실적으로 응용 가능한 시스템의 개발은 해당 분자 정보의 특성 에 잘 맞는 새로운 모델과 정보 표현 방법, 그리고 새로운 기본 연산자의 도입을 필요로 한다. 본 논문 에서는 다양한 패턴 분석 모델의 기본연산이라 할 수 있는 가중치 합 연산의 분자 컴퓨팅 버전을 제시하 는...

Entangled polymer melts exhibit a variety of flow instabilities that limit production rates in industrial applications. We present both experimental and computational findings, using flow of monodisperse linear polystyrenes in a contraction-expansion geometry, which illustrate the formation and development of one such flow instability. This viscoelastic disturbance is observed at the slit outle...

The combinatorial nature of many important mathematical problems, including nondeterministic-polynomial-time (NP)-complete problems, places a severe limitation on the problem size that can be solved with conventional, sequentially operating electronic computers. There have been significant efforts in conceiving parallel-computation approaches in the past, for example: DNA computation, quantum c...

CONSPECTUS: Nucleic acids have become powerful building blocks for creating supramolecular nanostructures with a variety of new and interesting behaviors. The predictable and guided folding of DNA, inspired by nature, allows designs to manipulate molecular-scale processes unlike any other material system. Thus, DNA can be co-opted for engineered and purposeful ends. This Account details a small...

In continuum approaches to molecular electrostatics, the boundary element method (BEM) can provide accurate solutions to the Poisson-Boltzmann equation. However, the numerical aspects of this method pose significant problems. We describe our approach, applying an alpha shape-based method to generate a high-quality mesh, which represents the shape and topology of the molecule precisely. We also ...

The next two decades will bring us silicon computation resources that seem unimaginable today. Advances in lithographic technology will enable devices with ten billion transistors and beyond. Surprisingly, the challenges that face traditional silicon computing are eerily similar to those molecular and other nanoscale devices must confront. The solution we propose for scalable silicon, the compu...