For glucose-lowering drugs inducing hypoglycemia, a marginally protective effect on the risk of MACE was observed for HbA1c 48-58 mmol/mol, whereas significant reduction microvascular complications HbA1c<49 but with higher severe hypoglycaemia. Drugs not hypoglycaemia were associated MACE, renal adverse events, and all-cause mortality, HbA1c<7% (no data lower targets). Conclusions: presen...

The title compound, C(17)H(21)NS, was prepared by the condensation of thio-phene-2-carbaldehyde with 2,6-diiso-propyl-aniline. It crystallizes with two mol-ecules in the asymmetric unit. The mol-ecules are inter-connected via a C-H⋯N hydrogen bond. The dihedral angles between the thio-phene and phenyl rings are 81.7 (7) and 85.5 (7)°.

The mol-ecule of the title compound, C(7)H(7)NO(3), is nearly planar [maximum deviation 0.112 (3) Å for one of the notro O atoms]. In the crystal structure, inter-molecular O-H⋯O and C-H⋯O inter-actions link the mol-ecules into a three-dimensional network.

In the mol-ecule of the title compound, C(7)H(7)ClO(2)S, the six-membered ring adopts a twisted conformation. In the crystal structure, weak inter-molecular C-H⋯O hydrogen bonds link the mol-ecules. There is also a weak C-H⋯π inter-action.

In the title mol-ecule, C(11)H(16)NO(6)P, the nitro group is twisted out of the mean plane of the benzene ring at 29.91 (3)°. The two ethyl groups are disordered between two orientations in the ratios 0.784 (7)/0.216 (7) and 0.733 (6)/0.267 (6). Inter-molecular O-H⋯O hydrogen bonds link the mol-ecules into centrosymmetric dimers.

Scoparia dulcis Linn plays an important role in treatment because it contains active compounds that are proven to have a variety of activities, including cytotoxicity on various cancer cells. The objective this study is isolate and identify the cytotoxic ethyl acetate fraction dulcis, observe cell cycle inhibition induction apoptosis vitro, carry out molecular studies using silico studies. A ne...

There are two symmetry-independent mol-ecules, A and B, in the asymmetric unit of the title compound, C(15)H(11)FO(3)S. The crystal studied was an inversion twin with a 0.21 (12):0.79 (12) domain ratio. In the crystal structure, the two independent mol-ecules are related by a pseudo-inversion center. The dihedral angles formed by the phenyl ring and the plane of the benzofuran fragment are 80.2...

The asymmetric unit of the title compound, C21H19N3O3S, contains two independent mol-ecules. In one mol-ecule, the 1,3-thia-zolidine ring forms dihedral angles of 86.19 (8) and 8.37 (8)° with the phenyl and benzene rings, respectively. The corresponding dihedral angles in the other mol-ecule are 69.60 (7) and 14.08 (7)°. The dihedral angle between the phenyl and benzene rings is 84.70 (8)° in o...

<p>Indonesia salah satu negara berkembang dengan besarnya populasi penduduk dan perkembangan aktifitas yang meningkat setiap tahunnya. Sehingga sampah dihasilkan tidak sebanding pengolahan ada. Pengelolaan baik selain mengganggu pemandangan lingkungan juga dapat berimbas pada kesehatan. Penelitian ini menganalisis efektifitas MOL bonggol pisang sisa nasi pembuatan kompos.</p><p&g...

The title compound, C(25)H(29)NO(3), is a Schiff base derivative of coumarin 120. There are two structurally similar but crystallographically independent mol-ecules in the asymmetric unit. Both mol-ecules exist in E configurations with respect to the C=N double bonds. The dihedral angles between the coumarin and 3,5-di-tert-butyl-2-hy-droxy-benzyl-idene ring planes are 4.62 (7) and 14.62 (7)° f...