Seven years of experience in compensator intensity-modulated radiotherapy (IMRT) clinical implementation are presented. An inverse planning dose optimization algorithm was used to generate intensity modulation maps, which were delivered via either the compensator or segmental multileaf collimator (MLC) IMRT techniques. The in-house developed compensator-IMRT technique is presented with the focu...

The use of intensity-modulated radiation therapy (IMRT) has led to an increase in the number of complex fields that require measurement and comparison to calculated dose distributions in 2D. Current dose-evaluation techniques, including isodose line comparisons, displays of the dose difference between calculated and measured distributions, and distance-to-agreement (DTA) comparisons, are useful...

background: an effective method for management of large and bulky malignant tumors. this treatment modality is also known as specially fractionated radiation therapy (sfrt). in this treatment technique a grid block converted the open radiation field into a series of pencil beams. dosimetric characteristics of an external beam grid radiation field have been investigated using experimental and mo...

Article history: Received 26 May 2011 Received in revised form 20 December 2011 Accepted 23 December 2011 Available online 2 January 2012

The recent development of intensity modulated radiation therapy (IMRT) allows the dose distribution to be tailored to match the tumour's shape and position, avoiding damage to healthy tissue to a greater extent than previously possible. Traditional treatment plans assume that the target structure remains in a fixed location throughout treatment. However, many studies have shown that because of ...

The quantitative comparison of two-dimensional dose distributions (e.g., calculated versus measured) has become a key issue in intensity-modulated radiotherapy (IMRT) QA. We proposed a new evaluation method referred to as modified dose difference (MDdiff) evaluation. Hereinafter, features and effectiveness of the MDdiff evaluation method will be described. In this work, the formalism of MDdiff ...

We consider Pareto surface based multi-criteria optimization for step and shoot IMRT planning. By analyzing two navigation algorithms, we show both theoretically and in practice that the number of plans needed to form convex combinations of plans during navigation can be kept small (much less than the theoretical maximum number needed in general, which is equal to the number of objectives for o...

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There is no consensus on whether luminance-modulated (LM) and contrast-modulated (CM) stimuli are processed by common or separate mechanisms. To investigate this, the sensitivity variations to these stimuli are generally compared as a function of different parameters (e.g., sensitivity as a function of the spatial or temporal window sizes) and similar properties have been observed. The present ...