hirchsprung’s disease is a developmental disorder of the enteric nervous system, characterized by abdsence of ganglion cell in the myenterric and submucosal plexuese along a variable portion of the distal intestine.the purpose of this study is the presentation of a new procedure for reduction of the postoperative complications of hirschsprung’s disease (hd) by offering a modified swenson’s tech...

background: visceral leishmaniasis is systematic serous parasitic disease with pub­lic health importance. zoonotic form of visceral leishmaniasis is wide spread in mediterranean basin and south america regions. direct agglutination test (dat) is an accurate, reliable and non-expensive serological test for the diagnosis of visceral leishmaniasis in human and canines but the antigen preparation i...

chromium (vi) adsorption behavior and capacity by surface modified nanozeolite a has been investigated. surface modification was performed and the morphology of modified and unmodified nanozeolite was studied using scanning electron microscope (sem) and transmission electron microscope (tem). adsorption isotherms were studied under different conditions (ph, adsorbent dose, adsorbate concentrati...

this paper provides an overview of how the surface properties of ferromagnetic nanoparticles dispersed in fluids is modified by natural and biocompatible polymers. among common magnetic nanoparticles, magnetite (fe3o4) and maghemite (g-fe203) are popular candidates because of their biocompatibility. natural polymeric coating materials are the most commonly used biocompatible magnetic nanopartic...

Hebbian synaptic plasticity acts as a positive feedback mechanism and can destabilize a neuronal network unless concomitant homeostatic processes that counterbalance this instability are activated. Within a Bienenstock-Cooper-Munro (BCM)-like plasticity framework, such compensation is achieved through a modification threshold that slides in an activity-dependent fashion. Although the BCM-like p...

Although hyperglycemia is causally related to adverse outcomes after myocardial ischemia/reperfusion (I/R), the underlying mechanisms are largely unknown. Here, we investigated whether excessive O-linked-N-acetylglucosamine (O-GlcNAc) modification of acetaldehyde dehydrogenase 2 (ALDH2), an important cardioprotective enzyme, was a mechanism for the hyperglycemic exacerbation of myocardial I/R i...

Endogenic modification in lunar floor-fractured craters can constrain spatial variations in early lunar conditions. The nature of these constraints, however, depends on the assumed mechanism of crater modification. For viscous relaxation, the extent of crater modification depends on the surrounding crustal viscosity and thus provides loose constraints on the history of crustal heating within a ...

Self-immolative linkers offer efficient mechanisms for deprotecting ‘caged’ functional groups in response to specific stimuli. Herein we describe a convenient ‘click’ chemistry method introducing pendant self-immolative polymer backbone through post-polymerization modification. The introduced triazole rings serve both anchor the stimuli-cleavable trigger backbone, while also forming part of sel...

Visual stimuli are known to induce various changes in the receptive field properties of adult cortical neurons, but the underlying mechanisms are not well understood. Repetitive pairing of stimuli at two orientations can induce a shift in cortical orientation tuning, with the direction and magnitude of the shift depending on the temporal order and interval between the pair. Although the tempora...