BACKGROUND We sought to determine the lifetime prevalence of traumatic brain injury and its association with current health conditions in a representative sample of homeless people in Toronto, Ontario. METHODS We surveyed 601 men and 303 women at homeless shelters and meal programs in 2004-2005 (response rate 76%). We defined traumatic brain injury as any self-reported head injury that left t...

natriuretic peptide (ANP) on hemodynamics, pulmonary gas exchange, and urine volume during mechanical ventilation with positive end-expiratory pressure (PEEP) in patients with acute lung injury. Design: Prospective, randomized, comparable study. Setting: ICU of a university hospital. Patients: Forty patients with moderate acute lung injury (lung injury score ^2.0) who required mechanical ventil...

Hypoxic brain injury can be a devastating complication of anesthesia. Fortunately, it has become increasingly rare. Here we report a case of suspected intraoperative hypoxic brain injury treated with moderate hypothermia. Anesthesiologists should be aware of the option of using this therapy and how to employ it in the setting of suspected hypoxic brain injury.

BACKGROUND Traumatic brain injury (TBI) is one of the leading causes of death and disability worldwide. The burden of TBI is greatest in low- and middle-income countries (LAMIC), yet little is known about patient outcomes in these settings. METHODS Complete data on 8927 patients from 46 countries from the corticosteroid randomization after significant head injury (CRASH) trial were analysed t...

Wound healing consists of three overlapping phases: inflammation, proliferation, and matrix synthesis and remodeling. Prolonged alcohol abuse can cause liver fibrosis due to deregulated matrix remodeling. Previous studies demonstrated that moderate ethanol feeding enhances liver fibrogenic markers and frank fibrosis independent of differences in CCl₄-induced liver injury. Our objective was to d...

OBJECTIVE To assess the exposure of players to injury risk during English Premier League soccer matches in relation to selected factors. METHODS Injury risk was assessed by rating the injury potential of playing actions during competition with respect to (a) type of playing action, (b) period of the game, (c) zone of the pitch, and (d) playing either at home or away. In all, 10 games from the...

OBJECTIVE To index the frequency of reported chronic pain in patients with traumatic brain injury (TBI). DESIGN A case series study was conducted on consecutive patients with TBI. SETTING TBI patients were recruited from an adult tertiary care center brain injury clinic. PATIENTS A consecutive sample of 132 patients who attended a brain injury rehabilitation center after TBI. The sample i...

BACKGROUND Head injury is the major cause of death in a neurosurgical patient. OBJECTIVE To find the outcome, and treatment modality affecting the outcome in patients with head injury. METHODS Nine hundred eighty seven patients presenting to National Institute of Neurological and Allied Sciences, Kathmandu, with head injury from September 2009 to October 2010 were included in the study. Pat...

OBJECTIVE To evaluate the outcomes of early comprehensive rehabilitation protocols for traumatic brain injury (TBI) using the functional independence measure (FIM), and to study the relationship between FIM and Glasgow coma scale (GCS) variables to determine which patients will be best served by rehabilitation therapies. METHODS Fifty-one subjects with diagnosed TBI receiving treatment at a s...