The infiltration term in the building energy balance equation is one of the least understood and most difficult to model. For many residential buildings, which have an energy performance dominated by the envelope, it can be one of the most important terms. There are numerous airflow models; however, these are not combined with whole-building energy simulation programs that are in common use in ...

BACKGROUND In experimental models of diabetes mellitus, aggravation of renal injury by concomitant hypertension has been described. Inflammatory mechanisms contribute to renal damage in both diseases. We investigated whether hypertension and diabetes mellitus act synergistically to induce macrophage infiltration and matrix expansion in the kidney. METHODS Insulin-dependent diabetes mellitus w...

Existing continuum models of multiphase flow in porous media are unable to explain why preferential flow (fingering) occurs during infiltration into homogeneous, dry soil. Following a phase-field methodology, we propose a continuum model that accounts for an apparent surface tension at the wetting front and does not introduce new independent parameters. The model reproduces the observed feature...

The effect of flow instabilities on capillary trapping mechanisms is a major source of uncertainty in CO2 sequestration in deep saline aquifers. Standard macroscopic models of multiphase flow in porous media are unable to explain and quantitatively predict the onset and structure of viscous-unstable flows, such as the displacement of brine by the injected CO2. We present the first step of a res...

Regulatory T cells (CD4+CD25+FoxP3+, Treg) have been shown to play a major role in suppression of the immune response to malignant gliomas. In this study, we investigated the kinetics of Treg infiltration in metastatic brain tumor models, including melanoma, breast and colon cancers. Our data indicate that both CD4+ and Treg infiltration are significantly increased throughout the time of metast...

OBJECTIVE To compare the diagnostic performance of six different approaches for assessing myometrial infiltration using ultrasound in women with carcinoma of the corpus uteri. METHODS Myometrial infiltration was assessed by two-dimensional (2D) transvaginal or transrectal ultrasound in 169 consecutive women with well (G1) or moderately (G2) differentiated endometrioid type endometrial carcino...

Differentiating tumor from normal brain is a major barrier to achieving optimal outcome in brain tumor surgery. New imaging techniques for visualizing tumor margins during surgery are needed to improve surgical results. We recently demonstrated the ability of stimulated Raman scattering (SRS) microscopy, a nondestructive, label-free optical method, to reveal glioma infiltration in animal models...

Animal treading can change soil physical properties, and thus is an important factor in hydrological modelling. We investigated the impacts of animal treading on infiltration by using a series of rainfall simulation experiments at Whatawhata Research Center, Waikato, New Zealand. The study identified significant variables for estimating soil steady-state infiltration at a microsite (0Ð5 m2) and...

T cell infiltration into the CNS is a significant underlying pathogenesis in autoimmune inflammatory demyelinating diseases. Several lines of evidence suggest that glutamate dysregulation in the CNS is an important consequence of immune cell infiltration in neuroinflammatory demyelinating diseases; yet, the causal link between inflammation and glutamate dysregulation is not well understood. A m...

Artificial recharge can be an effective method to raise the groundwater table and to resolve the groundwater crisis in Sefid dasht plain. The most important step to successful accomplishment of artificial recharge is locating suitable areas for artificial recharge. Hence this research carried out with purpose of determining suitable areas for artificial recharge in Sefid dasht plain. Slope, sur...