Exposure to excessive levels of manganese (Mn) is associated with the development of movement disorders, with symptoms overlapping with Parkinson's disease. Oxidative damage has been implicated as a key contributor to Mn-induced neurotoxicity. We have recently reported that divalent Mn (Mn(2+)) stimulates brain microglia to produce and release hydrogen peroxide (H2O2), and microglial-free radic...

This paper presents the reinforcement of nanocellulose (NC) in polyvinyl alcohol (PVA) to examine effect amount on properties PVA. The was successfully extracted by sulfuric acid hydrolysis method and ultrasonication, successively reinforced with solvent-casting method. After incorporating into PVA matrix, tensile strength, elongation at break, water absorption capacity, transmittance, thermal ...

A library of 10 Mn-containing complexes capable of switching reversibly between the Mn(II) and Mn(III) oxidation states was prepared and evaluated for potential usage as MRI reporters of tissue redox activity. We synthesized N-(2-hydroxybenzyl)-N,N',N'-ethylenediaminetriacetic acid (HBET) and N-(2-hydroxybenzyl-N,N',N'-trans-1,2-cyclohexylenediaminetriacetic acid (CyHBET) ligands functionalized...

In this combined X-ray diffraction and photoluminescence study, the coordination environment of Mn(2+) and the photoluminescence of single Mn(2+) doped KMgBO3 phosphors were studied. Mn(2+) occupies Mg(2+) sites, which were coordinated by six O(2-). The strong absorption of KMgBO3:Mn(2+) was ascribed to the strong relaxation of spin and parity forbidden d-d transitions of Mn(2+). The emission b...

Activation of a water molecule by the electrochemical oxidation of a Mn-aquo complex accompanied by the loss of protons is reported. The sequential (2 × 1 electron/1 proton) and direct (2 electron/2 proton) proton-coupled electrochemical oxidation of a non-porphyrinic six-coordinated Mn(II)OH2 complex into a mononuclear Mn(O) complex is described. The intermediate Mn(III)OH2 and Mn(III)OH compl...

In order to study the effect of different levels of the manure and foliar application of Zn and Mn fertilizers on the quantitative and qualitative yield of soybeans (var. Williams), a factorial experiment was conducted in a randomized complete block design with three replications in 2012. Treatments involved three levels of fertilizer: manure (zero as control; six and 12 t/ha), two lev...

The oxygen-evolving complex (OEC) of photosystem II contains a Mn(4)CaO(n) catalytic site, in which reactivity of bridging oxidos is fundamental to OEC function. We synthesized structurally relevant cuboidal Mn(3)MO(n) complexes (M = Mn, Ca, Sc; n = 3,4) to enable mechanistic studies of reactivity and incorporation of μ(3)-oxido moieties. We found that Mn(IV)(3)CaO(4) and Mn(IV)(3)ScO(4) were u...

Imperfect performance equilibrium is defined as a Nash equilibrium where the players' actions may involve non-infinitesimal random errors: each player is endowed with a personal behavior pattern {his, performancefunction) under which the action that he takes depends stochastically on (i) what the player sets out to do, and (ii) the potential consequences that can accrue to him from each of his ...

Anomalous origin of left coronary artery from pulmonary artery (ALCAPA) or the Bland-White-Garland syndrome was first described in the year 1866 and postulated in 1933. It is an intriguing entity in the field of paediatrics as well as paediatric cardiology due to its varied presentation in the paediatric age group. This congenital heart anomaly is reported in less than 0.5% of all the congenita...