The first 50 years of Integer and Mixed-Integer Programming have taken us to a very stable paradigm for solving problems in a reliable and effective way. We run over these 50 exciting years by showing some crucial milestones and we highlight the building blocks that are making nowadays solvers effective from both a performance and an application viewpoint. Finally, we show that a lot of work mu...

This work addresses the optimization of ammonia–water absorption cycles for cooling and refrigeration applications with economic and environmental concerns. Our approach combines the capabilities of process simulation, multi-objective optimization (MOO), cost analysis and life cycle assessment (LCA). The optimization task is posed in mathematical terms as a multi-objective mixed-integer nonline...

Most of the available literature on optimal well placement has employed numerical simulators in a black box manner linked to an external search engine. In this work, we formulate the contents of that box inside a mixed integer nonlinear programming model for optimal well placement. We provide a unified model that integrates the subsurface, wells, and surface levels of an upstream production pro...