A novel and environmentally benign approach is described to combine reactions and separations, using simultaneously ionic liquids (ILs) and supercritical carbon dioxide (SCCO2). The novel approach is based on the phenomenon that two (partially) immiscible liquid phases upon pressurization with CO2 is able to force to form one homogeneous fluid phase. The homogeneous phase allows reactions to be...

We report the phase behaviour of polymer/fullerene/solvent ternary mixtures and its consequence for the morphology of the resulting composite thin films. We focus particularly on solutions of polystyrene (PS), C60 fullerene and toluene, which are examined by static and dynamic light scattering, and films obtained from various solution ages and thermal annealing conditions, using atomic force an...

Analytic and numerical microscopic integral equation theory for polymer–particle suspensions is employed to investigate the dependence of fluid–fluid phase separation on size asymmetry, solvent quality, and higher order polymer–polymer interactions. For athermal good solvents, our prior novel prediction of enhanced miscibility with increasing ~decreasing! polymer ~particle! size is found not to...

Knowledge of the glass transition temperatures (Tgs) as function of composition reflects miscibility (or lack of it) and is decisive for virtually all properties of polymer-based materials. In this article, we analyze single blend-average and effective Tgs of miscible polymer blends in full concentration ranges. Shortcomings of the extant equations are discussed to support the need for an alter...

Submitted for the MAR09 Meeting of The American Physical Society Miscibility Critical Points in Plasma Membranes BENJAMIN MACHTA, SARAH VEATCH, STEFANOS PAPANIKOLAOU, JAMES P. SETHNA, Cornell University — Lipid bilayers surround all cells and are home to a host of proteins and lipids that mediate interactions between the cell and its environment. Recent experimental work has shown that simple m...

OBJECTIVE The present paper describes an in silico solubility behavior of drug and lipids, an essential screening study in preparation of solid lipid nanoparticles (SLN). MATERIALS AND METHODS Ciprofloxacin HCl was selected as a model drug along with 11 lipids and 5 organic solvents. In silico miscibility study of drug/lipid/solvent was performed using Hansen solubility parameter approach cal...

Bovine plasma proteins provide the needed amino acids for the growth and development of an organism. With the purpose of preserving the native structure, related with the protein functional properties, the oligosaccharide inulin was used as protective agent and was compared with glucose and sucrose, during freeze-drying. In the present study, the thermal stability of protein was investigated as...