نتایج جستجو برای: mir 144

تعداد نتایج: 59358  

2012
Marian Grade Jordi Camps Rolf Søkilde Bogumil Kaczkowski Aaron J. Schetter Michael J. Difilippantonio Curtis C. Harris B. Michael Ghadimi Søren Møller Tim Beissbarth Thomas Litman

Purpose: miRNAs play a prominent role in a variety of physiologic and pathologic biologic processes, including cancer. For rectal cancers, only limited data are available on miRNA expression profiles, whereas the underlying genomic and transcriptomic aberrations have been firmly established. We therefore, aimed to comprehensively map the miRNA expression patterns of this disease. Experimental D...

2016
Mi-Hyun Kim Jeong Su Cho Yeongdae Kim Chang Hun Lee Min Ki Lee Dong Hoon Shin

Lung adenocarcinomas can be classified into terminal respiratory unit (TRU) and non-TRU types. We previously reported that non-TRU-type adenocarcinoma has unique clinical and morphological features as compared to the TRU type. Here we investigated whether micro (mi)RNA expression profiles can be used to distinguish between these two subtypes of lung adenocarcinoma. The expression of 1205 human ...

2013
Gretchen van Steenwyk Paulina Janeczek Joanne M. Lewohl

Chronic and excessive alcohol misuse results in changes in the expression of selected miRNAs and their mRNA targets in specific regions of the human brain. These expression changes likely underlie the cellular adaptations to long term alcohol misuse. In order to delineate the mechanism by which these expression changes occur, we have measured the expression of six miRNAs including miR-7, miR-15...

2017
Tao Wang Haihe Xu Xianglong Liu Shuo Chen Yi Zhou Xipeng Zhang

BACKGROUND The aim of this study was to screen the molecular targets of miR-34a in colorectal cancer (CRC) and construct the regulatory network, to gain more insights to the pathogenesis of CRC. MATERIAL AND METHODS The microarray data of CRC samples and normal samples (GSE4988), as well as CRC samples transformed with miR-34a and non-transfected CRC samples (GSE7754), were downloaded from the ...

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