نتایج جستجو برای: microrna 23b
تعداد نتایج: 37676 فیلتر نتایج به سال:
The management of cerebral glioma (CG) remains challenging. Recently, methods based on the study expression levels miRNAs in blood plasma have proven to be promising. volume tumor tissue is known correlate with increased microRNA-21 and -210. MicroRNA-15, -16, -34, -126 -342 are involved regulation proliferative potential, microRNA-128 metabolic activity. aim was evaluate extended protocol for ...
BACKGROUND Several potential predictive markers of efficacy of targeted agents in patients with metastatic renal cell carcinoma (mRCC) have been identified. Interindividual heterogeneity warrants further investigation. PATIENTS AND METHODS Multicenter, observational, retrospective study in patients with clear-cell mRCC treated with sunitinib. Patients were classified in two groups: long-term ...
Effect and Association of circ_0084927 and microRNA-634 on Lung Cancer Cell Sensitivity to Cisplatin
To investigate the role of circ_0084927 in lung cancer cell sensitivity to cisplatin. Half-maximal inhibitory concentration value cisplatin was detected by counting kit-8. and microRNA-634 expression were determined reverse transcription quantitative polymerase chain reaction. Cell kit-8, scratch healing, colony formation as well Transwell experiments used for analyzing viability, healing rate,...
in the retinoblastoma research, it is of great interest to identify molecular markers associated with the genetics of tumorigenesis. micrornas (mirnas) are small non-coding rna molecules that play a regulatory role in many crucial cellular pathways such as differentiation, cell cycle progression, and apoptosis. a body of evidences showed dysregulation of mirnas in tumor biology and many disease...
objective: the aim of the present study was the production of recombinant lentviruses that express mir-16. after transduction, altered expression levels of mirna and its target protein were analyzed. methods: a dna fragment that contained the mir-16 precursor was cloned in a lentiviral plasmid. lentiviral vector particles were produced by transient calcium phosphate co-transfection of 293t cell...
سرطان، نتیجه ی عملکرد نادرست ژنوم و تغییر الگوی بیان ژنی در سلول هاست. در بیشتر سرطان های سینه، یکی از ژن هایی که افزایش بیان نشان می دهد، ژن tpd52 (tumor protein d52) است. این افزایش بیان، باعث افزایش رشد مستقل از سطح سلول ها می شود. بنابراین، شاید با کاهش بیان این ژن، بتوان به درمان این سرطان ها کمک کرد. یکی از روش های کاهش بیان ژن ها، مهار پس از رونویسی آن ها و یک روش نوین این کار، استفاده ا...
ABSTRACT We report the discovery of three new hot Jupiters with Next Generation Transit Survey (NGTS) as well updated parameters for HATS-54b, which was independently discovered by NGTS. NGTS-23b, NGTS-24b, and NGTS-25b have orbital periods 4.076, 3.468, 2.823 d orbit G-, F-, K-type stars, respectively. NGTS-24 HATS-54 appear close to transitioning off main-sequence (if they are not already doi...
Bacterial blight (BB), caused by Xanthomonas oryzae pv.oryzae is one among the major diseases in rice, which in severe condition cause losses up to 60% in total yield. Marker assisted pyramiding of three broad spectrum BB resistance genes (xa5, xa13, and Xa21) in prominent rice varieties is the most economical and effective strategy for the management of the BB disease. We report here the pyram...
To investigate the mechanism of lidocaine in inhibiting proliferation, migration and invasion breast cancer cells. Human cell line Michigan Cancer Foundation-7 cells were treated with lidocaine. Cell proliferation was detected by 2,5-diphenyl-2H-tetrazolium bromide, Transwell, microRNA-495-3p expression quantitative reverse transcription polymerase chain reaction fibroblast growth factor 9, cyc...
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