Sustained price increases for traditional cereal grain and protein meal feed commodities have forced the pork industry to consider the dietary inclusion of alternative feedstuffs. Crop seed may serve as feedstuffs but their demand as feedstock for human food, biofuel, and bioindustrial products has increased. Together with these products, coproducts such as distillers dried grains with solubles...

Many aesthetic and functional problems of skin, such as cutaneous dryness and atopical dermatitis, are due to reduced amount of lipids in the external skin layer. These diseases can be resolved by using topical creams containing balanced mixtures of epidermal lipids. However, the set up of a suitable process for obtaining epidermal lipid based formulations represents a key step to yield an effe...

Ethylene vinyl acetate blends (EVA-B) (at 19 and 28 wt% acetate) were supplied by the footwear industry, along with an industrial (reference) compound labeled EVA-ref. EVA waste is sub-product crosslinked (injection sprues unused midsoles), that was particulate through a micronization process as EVA-w. The objective of present work to evaluate processability rheological parameters (using torque...

Introduction . The low solubility of active pharmaceutical ingredients (APIs) in the physiological pH range intestinal tract can adversely affect their absorption and bioavailability. Various methods increasing APIs have been proposed recent decades. Among them there are preparation solid dispersions, micronization, solubilization other methods, including ones based on amorphization crystalline...

BACKGROUND Cellulose acetate phthalate (CAP) has been used for several decades in the pharmaceutical industry for enteric film coating of oral tablets and capsules. Micronized CAP, available commercially as "Aquateric" and containing additional ingredients required for micronization, used for tablet coating from water dispersions, was shown to adsorb and inactivate the human immunodeficiency vi...

Historically, pharmaceutical aerosols have been employed for the treatment of obstructive airway diseases, such as asthma and chronic obstructive pulmonary disease, but in the past decades their use has been expanded to treat lung infections associated with cystic fibrosis and other respiratory diseases. Tuberculosis (TB) is acquired after inhalation of aerosol droplets containing the bacilli f...

It is well established that sun exposure is the main cause for the development of skin cancer. Chronic continuous UV radiation is believed to induce malignant melanoma, whereas intermittent high-dose UV exposure contributes to the occurrence of actinic keratosis as precursor lesions of squamous cell carcinoma as well as basal cell carcinoma. Not only photocarcinogenesis but also the mechanisms ...

The best bile acid therapy currently available is ursodeoxycholic acid (UDCA), which is a bile salt that both reduces the secretion of cholesterol into bile and increases cholesterol solubility. The aim of this study is to compare pharmacokinetic parameters as well as relative bioavailability of the developed enteric coated tablet of UDCA 300 mg prepared from micronized drug (MCUDCA) with respe...

We studied the influence of enzyme supplementation (ES) of the diet and heat processing (HP) of barley on digestive traits and productive performance of broilers from 1 to 42 d of age. There were 6 diets arranged factorially with 2 doses (0 and 500 ppm) of a fungal enzyme complex with beta-glucanase and xylanase activity and 3 HP of barley (raw, micronized, and expanded). In addition, a control...