Mixing two immiscible liquids (such as oil and water) using emulsifier and energy inputs has been the matter of study for decades. In early 1890’s extensive work have been carried out on macroemulsions (i.e. oil dispersed in water in the form of fine droplets or vice versa) (Becher, 1977) and several theories and methods of their formation have been vastly explored (Lissant 1976 and 1984). Howe...

the paper is focused on the formation of calcium phosphate nanoparticles (cp) in polyelectrolyte-modified microemulsions, in a microemulsion template phase consisting of cyclohexane, water, anionic surfactantant and cosurfactant, in the presence of anionic and cationic polyelectrolyte. it is shown that polyelectrolyte, can be incorporated into the individual inverse microemulsion droplets. the ...

Clopidogrel, an inhibitor of platelet aggregation, selectively inhibits the binding of adenosine diphosphate (ADP) to its platelet receptor and the subsequent ADP-mediated activation of the glycoprotein GPIIb/IIIa complex, thereby inhibiting platelet aggregation. Oral bioavailability of clopidogrel is very low (less than 50%), due to its poor water solubility. The aim of this investigation was ...

Clopidogrel, an inhibitor of platelet aggregation, selectively inhibits the binding of adenosine diphosphate (ADP) to its platelet receptor and the subsequent ADP-mediated activation of the glycoprotein GPIIb/IIIa complex, thereby inhibiting platelet aggregation. Oral bioavailability of clopidogrel is very low (less than 50%), due to its poor water solubility. The aim of this investigation was ...

in this study, tretinoin microemulsion has been formulated based on phase diagram studies by changing the amounts and proportions of inactive ingredients, such as surfactants, co-surfactants and oils. the effects of these variables have been determined on microemulsion formation, particle size of the dispersed phase and release profile of tretinoin from microemulsion through dialysis membrane. ...

Clove bud essential oil (CEO) and its major individual phenolic constituent eugenol were formulated as nanoparticles in water-based microemulsion systems. The oil titration method was used to incorporate different amounts of the oil and eugenol in the micellar solution of Tween-20. The Antioxidant and antimicrobial activities were evaluated using the DPPH* free radical scavenging assay and the ...

Turing structures, standing waves, oscillatory clusters, and accelerating waves have been found in the spatially extended Belousov-Zhabotinsky system dispersed in water droplets of a reverse AOT microemulsion. The variety of patterns is determined by the tunable microstructure of the medium, i.e., by the concentration and size of water droplets. We propose a simple model to describe this system.

A new electrochemical method to synthesize mesoporous nanowires of alloys has been developed. Electrochemical deposition in ionic liquid-in-water (IL/W) microemulsion has been successful to grow mesoporous CoPt nanowires in the interior of polycarbonate membranes. The viscosity of the medium was high, but it did not avoid the entrance of the microemulsion in the interior of the membrane's chann...

Essential oil extracted from Houttuynia cordata Thunb. (H. cordata) is widely used in traditional Chinese medicine due to its excellent biological activities. However, impurities and deficient preparations of the essential oil limit its safety and effectiveness. Herein, we proposed a strategy to prepare H. cordata essential oil (HEO) safely and effectively by combining the solvent extraction an...

Objective(s):The objective of this study was to find a stable microemulsion vehicle for transdermal delivery of ibuprofen to improve the skin permeability. Materials and Methods: Microemulsion was prepared using different sorts of oils, surfactants and co-surfactants. Pseudo-ternary phase diagrams were used to evaluate the microemulsion domain. The effects of oleic acid and surfactant mixture o...