mucosa-adhesive gels can be used as a useful mean of delivering drugs to or via mucosal membranes, and in particular buccal mucosa. carbomers are among the best mucosa-adhesive materials known. the aim of this study was to compare the results obtained from the mucosa-adhesive strength of aqueous gels containing carbomers, either alone or in combination, to the data obtained from assessing the d...

A topical preparation containing aceclofenac was developed using an o/w microemulsion system. Isopropyl myristate was chosen as the oil phase as it showed a good solubilising capacity. Pseudo-ternary phase diagrams were used to obtain the concentration ranges of the oil, surfactant (Labrasol) and co-surfactant (plurol oleique) for microemulsion formation. Five different formulations were formul...

Abstract Background Treatment in neurological disorders like schizophrenia requires continuous presence of drug the brain for a prolonged period time to achieve an effective therapeutic response. Delivery antipsychotic quetiapine form conventional delivery systems suffers from low oral bioavailability, first-pass metabolism, and frequent dosing. In addition that biological obstacles present at ...

A general approach for producing biodegradable nanoparticles for sustained nucleic acid release is presented. The nanoparticles are produced by precipitating a water-in-oil microemulsion in supercritical CO(2). The microemulsion consists of a transfer RNA aqueous solution (water phase), dichloromethane containing poly(l-lactic acid)-poly(ethylene glycol) (oil phase), the surfactant n-octyl β-D-...

Two binary oxides, a spinel, ZnAl2O4, and a typical perovskite, LaMnO3, have been prepared via CTAB-1-butanol-n-octane-nitrate salt microemulsion in the reverse and bicontinuous states. The exact point of the reverse and bicontinuous states of the microemulsion used in the synthesis was determined by conductivity experiments. The materials obtained after heating at 800 degrees C were characteri...

Citation: Bera T, Malcuit C, Clements RJ and Hegmann E (2016) Role of Surfactant during Microemulsion Photopolymerization for the Creation of Three-Dimensional Liquid Crystal Elastomer Microsphere Spatial Cell Scaffolds. Front. Mater. 3:31. doi: 10.3389/fmats.2016.00031 role of surfactant during Microemulsion Photopolymerization for the creation of Three-Dimensional liquid crystal elastomer Mic...

Microemulsion represents an attractive platform for fundamental and applied biomedical research because the emulsified droplets can serve as millions of compartmentalized micrometer-sized reactors amenable to high-throughput screening or online monitoring. However, establishing stable emulsions with surfactants that are compatible with biological applications remains a significant challenge. Mo...

Microemulsion-based organogels (MBGs) were effectively employed for the immobilization of four commonly used lipases. During the asymmetric hydrolysis of ketoprofen vinyl ester at 30 °C for 24 h, lipase from Rhizomucor miehei and Mucor javanicus immobilized in microemulsion-based organogels (RML MBGs and MJL MBGs) maintained good enantioselectivities (eep were 86.2% and 99.2%, respectively), an...

The objective of the existing research was formulation development and preparation microemulsion loaded emulgel in augmenting topical delivery Lornoxicam. Emulsion gel combined are recognized as Emulgels. Gelling agents Carbopol 940, 974, 980 were used to formulating Lornoxicam emulgel. drug release from determined depending on different gelling agents. Clove oil for internal phase Polyethylene...