Flurbiprofen, a potent nonsteroidal anti-inflammatory drug, is widely used for relief of pain in patients suffering from rheumatic diseases, migraine, sore throat and primary dysmenorrheal. However, this drug has many gastrointestinal side effects produced by its oral administration, such as gastric bleeding and peptic ulcer. These effects were responsible for non-compliance among patients, whi...

A topical preparation containing aceclofenac was developed using an o/w microemulsion system. Isopropyl myristate was chosen as the oil phase as it showed a good solubilising capacity. Pseudo-ternary phase diagrams were used to obtain the concentration ranges of the oil, surfactant (Labrasol) and co-surfactant (plurol oleique) for microemulsion formation. Five different formulations were formul...

Conventional oil extraction method involves various volatile organic solvents (VOCs) that are considered as toxic and probable carcinogenic solvents. Though the risk to human health and environmental contamination exist while using these organic solvents in various processes, they are primarily being used on the back of their easy availability. Additionally, due the absence of any pretreatment,...

This study aimed to evaluate a microemulsion system (ME) containing phenobarbital in epilepsy model induced by pilocarpine in rats and to oxidative stress and histologic lesions in hippocampus. The microemulsion was applied to the shaved back of Wistar rats. The animals were divided into the following groups: control group (P400); ME50 40mg/kg, topically-t.p.; ME100, 40mg/kg, t.p.; EM50, 40mg/k...

Microemulsions have received great attention for applications in transdermal drug delivery. The use of curcumin for treating various skin diseases like scleroderma, psoriasis, and skin cancer was extensively reported. The solubility of curcumin in various oils, surfactants, and cosurfactants was studied herein in order to find the optimal components for a transdermal delivery vehicle. Microemul...

a topical preparation containing aceclofenac was developed using an o/w microemulsion system. isopropyl myristate was chosen as the oil phase as it showed a good solubilising capacity. pseudo-ternary phase diagrams were used to obtain the concentration ranges of the oil, surfactant (labrasol) and co-surfactant (plurol oleique) for microemulsion formation. five different formulations were formul...

Electrolysis in microemulsions is a promising approach for environmentally friendly chemical synthetic methods of the future. Employing microemulsions instead of organic solvents for electrosynthesis has the advantages of lower toxicity and cost, high dissolving power for reactants and mediators of unlike solubility, enhancement of reaction rates by controlling the reduction potentials of media...

We report the synthesis of ZnSe:Mn quantum dots (QDs) in the dispersed phase of a microemulsion template consisting of p-xylene as the continuous phase, water as the dispersed phase, and an amphiphilic block copolymer (Pluronic P105) as the surfactant. The Zn and Mn precursors were Zn-acetate and Mn-acetate, respectively, dissolved in the aqueous dispersed phase. Hydrogen selenide gas was bubbl...

ABSTRACT: This research aims to prepare microemulsion from Tea Tree and Rosemary essential oil treat gram-positive gram-negative bacterial infections. A phase titration has been used make the proposed microemulsion, which contained 71% water, 23% of a 1:1 mixture propylene glycol (surfactant), tween 80 (co-surfactant), 6% tea tree/rosemary oil. In pale yellowish transparent droplet size, zeta p...

A topical preparation containing aceclofenac was developed using an o/w microemulsion system. Isopropyl myristate was chosen as the oil phase as it showed a good solubilising capacity. Pseudo-ternary phase diagrams were used to obtain the concentration ranges of the oil, surfactant (Labrasol) and co-surfactant (plurol oleique) for microemulsion formation. Five different formulations were formul...