A study of the presence of hepatitis A virus (HAV) and enterovirus (EV) in shellfish from the northwestern coast of Spain, one of the most important mussel producers in the world, was carried out employing dot-blot hybridization and RT-PCR techniques. In addition, bacterial contamination of the samples was evaluated by Escherichia coli (EC) counts, according to the European Union (EU) standards...

Contamination of pharmaceuticals with microorganisms may lead to deleterious effects on the therapeutic properties of the drug, and may potentially cause injuries to intended recipients. Cases of contaminated nonsterile products have been reported in increasing numbers, and often associated with the presence of objectionable microorganisms. Methods for detection of these organisms are described...

Alberta Vandini1, Alessia Frabetti1, Paola Antonioli2, Daniela Platano3, Alessio Branchini4, Maria Teresa Camerada1, Luca Lanzoni1, Piergiorgio Balboni1 and Sante Mazzacane1* 1CIAS Laboratory, Centre for the Study of Physical, Chemical and Microbiological Contamination of Highly Sterile Environments, Department of Architecture, University of Ferrara, Italy 2Infection Prevention Control and Risk...

Microbiological testing is a critical aspect of the development and evaluation medical devices, as it plays vital role in ensuring their safety efficacy. This article highlights importance microbiological device various types tests that are commonly performed. essential for assessing potential risks associated with such bacterial contamination or infections. Testing can also help to identify so...

So, 21 CFR 211.113 limits the discussion to “products not required to be sterile” and 21 CFR211.84 states that the concern is “microbiological contamination that is objectionable in view of its intended use” leaving 21 CFR 211.165 to require lab testing relevant to “drug product required to be free of objectionable microorganisms”. This clearly defined concept of an “objectionable” organism the...

In May 2010, a cluster of three cases of Legionnaires' disease was identified in France. The results of the epidemiological, environmental and microbiological investigations allowed the rapid identification of a public whirlpool spa as the most probable source of contamination and the implementation of appropriate control measures. This investigation has stressed the need for good cooperation b...

Introduction: Halvi is a traditional dairy product made from sheep milk in Mazandaran province, especially in the mountainous areas of Noor and Kojur. The fungus used in the preparation of Halvi is Auricularia auricula-judae. The present study aimed to investigate the chemical composition and microbiological properties of Halvi samples produced in various regions in No...

UNLABELLED This study investigated the capability of three rapid microbiological methods to detect microorganisms in aseptically prepared pharmacy preparations at National Health Service hospitals in the United Kingdom. BacT/ALERT 3D (bioMerieux), AKuScreen (Celsis), and BactiFlow ALS (AES Chemunex) technologies were used to detect levels of microorganisms in pharmaceutical products. Four produ...

AIMS   The optimal method for diagnostic collection of urine in children is unclear. National Institute of Health and Clinical Excellence recommend specimens taken by clean catch urine (CCU) for identification of urinary tract infection (UTI). We investigated contamination rates for CCU, suprapubic aspiration (SPA), catheter specimen urine (CSU) and bag specimen urine (BSU) collections. METHO...

Mycotoxins are unavoidable contaminants of food grains, feeds, medicinal herbs, and spices, posing as health threat to animals and humans. The objective of this study was to screen medicinal herbs and spices for fungi and mycotoxin contamination and evaluate their safety. Sixty-three samples were examined for fungal contamination and fungal load determined using standard microbiological method....