This study was carried out to investigate the potential use of Artemisia arborescens as a source of antimicrobial agents against pathogens. Essential oils of A. arborescens were collected by hydrodistillation. The antibacterial properties of A. arborescens essential oil was studied on the standard gram-negative bacteria (Escherichia coli and Pseudomonas aeruginosa), and Staphylococcus aureus (g...

Essential oils present a fine antibacterial performance against a variety of bacteria. The main component of the cinnamon oil was eugenol (75.52%). In this study, the goal was to evaluate the antimicrobial activity and reveal bactericidal mechanism of cinnamon oil. Firstly, the minimum inhibitory concentration (MIC) and the minimum bactericide concentration (MBC) of cinnamon oil were tested. Th...

A new class of highly functionalized tetrahydroisoquinolines with a quaternary carbon stereocenter was synthesized starting from an easily accessible L-tartaric acid. Nine strains of bacteria (Staphylococcus aureus, Streptococcus pyogenes, Streptococcus mutans, Streptococcus salivarius, Bacillus subtilis, Enterococcus faecalis, Moraxella catarrhalis, Escherichia coli, Campylobacter jejuni) were...

The spread of drug-resistant pathogens worldwide has spurred experts' interest in drug discovery. Medicinal plants are an essential source antimicrobial agents to cure various human ailments. Even though several have been examined for compounds, the search better and safer drugs combat microbial resistance continues. leaves oils Melaleuca cajuputi subject many investigations on plant's bioactiv...

BACKGROUND AND AIMS The emergence of novel diseases caused by microbial pathogens and the undesirable side effects of certain antibiotics has been a recent dilemma in the medical arena. Consequently, it has stirred the discovery of many naturally occurring agents which could possibly provide important ramifications against various pharmacological targets and to combat various ailments. The main...

OBJECTIVES The Burkholderia cepacia complex (Bcc) species are important opportunistic pathogens with intrinsic antibiotic resistance. They are also well known as contaminants of disinfectants, yet their biocide susceptibility has not been studied in detail. We investigated Bcc biocide susceptibility and correlated it to their taxonomy, antibiotic susceptibility and ability to form biofilms. M...

MICs are commonly used to assess the in vitro activities of antimicrobial agents; however, they provide minimal information on the pattern of bacterial activities. Time-kill studies with extensive sampling allow assessment of both the rate and extent of bacterial killing and regrowth. We compared imipenem and meropenem by both MIC-MBC testing and a time-kill study with P. aeruginosa 27853. In t...