INTRODUCTION Preoperative accurate localization of enlarged adenoma (s) in primary hyperparathyroidism (PHPT) is a vital necessity. Technetium 99m sestamibi scanning is commonly used with reported acceptable sensitivities; however, false negative scan studies remain a problem. Determining effective factors on the sensitivity of the scan might improve the diagnostic value of the study by selecti...

A 10-yr-old boy visited Minoh City Hospital complaining of gross hematuria. Laboratory investigations revealed hypercalcemia, hypophosphatemia, and elevated serum levels of parathyroid hormone. A stone was found in the right ureter with drip infusion pyelography. A parathyroid adenoma was successfully diagnosed with computed tomography, ultrasonography, and methoxy-2-isobutyl isonitrile (MIBI) ...

dilatation of a segment of the coronary artery to a diameter of at least 1.5 times that of normal adjacent segments.1 It is a well recognized, albeit rare, finding at cardiac catheterization. Clinical Objective: Coronary artery ectasia (CAE) is the abnormal dilatation of a segment of the coronary artery to a diameter of at least 1.5 times that of normal adjacent segments. Symptoms are variable,...

We report here a rare case of primary hyperparathyroidism that was associated with an ectopic parathyroid adenoma located in the mediastinum. A 66-year-old woman suffering from primary hyperparathyroidism had been followed-up on an outpatient basis for over 10 years. She suffered from persistent urolithiasis and osteopenia due to hypercalcemia. After technetium-99-sestamibi (99mTc-MIBI) scintig...

A 67-year-old man with elevated serum immunoglobulin G4 (IgG4) levels, systemic lymphadenopathy infiltrated by IgG4-positive plasma cells, and Coombs-positive autoimmune hemolytic anemia (AIHA) showed marked hypercalcemia. Although the intact parathyroid hormone (PTH) level was elevated, 99mTc-MIBI scintigraphy and thyroid ultrasonography revealed no evidence of primary hyperparathyroidism. Liv...

Multiple endocrine neoplasia type 1 (MEN1 or Wermer syndrome) is a rare hereditary disease, and especially its association with ectopic parathyroid adenomas even more. Defined As tumor developing in at least two glands including the anterior pituitary gland, duodeno-pancreatic tissue. This autosomal dominant pathology caused by mutation of NEM1 gene encoding suppressor menin located on chromoso...

objective: we sought to determine the usefulness of the 99mtc-mibi (mibi) washout rate for the evaluation of steroid therapy in cardiac sarcoidosis (cs). methods: eleven cs patients underwent mibi myocardial spect both before and 6 months after initiating steroid therapy. the washout rate (wor) of mibi was calculated using early and delayed polar map images. the washout score (wos) of mibi was ...