We have investigated here the mechanism of dephosphorylation and activation of death-associated protein kinase (DAPK) and the role of lysosome in neuroblastoma cells (SH-SY5Y) treated with mitochondrial toxins, such as MPP(+) and rotenone. Mitochondrial respiratory chain inhibitors and uncouplers decreased mitochondrial membrane potential leading to DAPK dephosphorylation and activation. The cl...

In previous work [Kovalets, I., Andronopoulos, S., Bartzis, J.G., Gounaris, N., Kushchan, A., 2004. Introduction of data assimilation procedures in the meteorological pre-processor of atmospheric dispersion models used in emergency response systems. Atmospheric Environment 38, 457–467.] the authors have developed data assimilation (DA) procedures and implemented them in the frames of a diagnost...

The recent woes of the supercomputer industry and changes in federal funding have caused some scientists to re-evaluate the means by which they hope to solve Grand Challenge problems. I evaluate the potential of Massively Parallel Processors (MPP) within this context and the state of today's MPP. I stress that for solving large-scale problems MPP are crucial and that it is essential to seek a b...

This paper shows the analytical performance of maximum power point tracking for a photovoltaic system. In contemplation for photovoltaic (PV) systems to escalate their efficiency of power generation, it is mandatory to locate the Maximum power point (MPP) under all possible illumination conditions. The current-voltage (I-V) characteristics of PV devices are non-linear in nature, thereby the , M...

In the course of screening for the anti-Parkinsonian drugs from a library of traditional herbal medicines, we found that the extracts of choi-joki-to and daio-kanzo-to protected cells from MPP+-induced cell death. Because choi-joki-to and daio-kanzo-to commonly contain the genus Glycyrrhiza, we isolated licopyranocoumarin (LPC) and glycyrurol (GCR) as potent neuroprotective principals from Glyc...

This paper describes an MPP UNIX in terms of goals, implementation and initial experience in using it lo port OLTP applications. Most MPP Unix systems strive towards the goal of a conventional but massively scaled up shared memory multiprocessor. In reality this goal has never been achieved without compromising scalability or fault-tolerance. The Infinity architeclure achieves scalability with ...

Objective: To analyze the clinical manifestations, laboratory values and treatment process of mycoplasma pneumoniae pneumonia (MPP) complicated with pulmonary embolism (PE) and provide a reference for the clinical diagnosis and management. Methods: We searched the electronic databases systematically to retrieve the relevant literatures. Results: A total of 17 articles about MPP complicated with...

A majority of the MPP systems designed to date have been MIMD distributed memory systems. For almost all of these systems, message passing environments have provided the primary mechanism for programming multiprocessor applications. In this paper we provide an introduction to MPP systems in general. We then introduce current MPP message passing interfaces, by tracing their historical developmen...

A 2.3-kb BamHI-KpnI fragment was isolated from a partial genomic library and shown by nucleotide sequence analysis to contain the entire coding region of the gene encoding the b subunit of the Blastocladiella mitochondrial processing peptidase (b-MPP). The predicted b-MPP protein has 465 amino acids and a calculated molecular mass of 50.8 kDa. S1 nuclease protection assays revealed an intron, 2...