OBJECTIVES To review the efficacy of cognitive interventions on improving general cognition in dementia. METHOD Online literature databases and trial registers, previous systematic reviews and leading journals were searched for relevant randomised controlled trials. A systematic review, random-effects meta-analyses and meta-regression were conducted. Cognitive interventions were categorised a...

CONTEXT Several studies have suggested that estrogen replacement therapy in postmenopausal women improves cognition, prevents development of dementia, and improves the severity of dementia, while other studies have not found a benefit of estrogen use. OBJECTIVE To determine whether postmenopausal estrogen therapy improves cognition, prevents development of dementia, or improves dementia sever...

BackgroundMultiple sclerosis (MS) is an immune-mediated demyelinating disease that disrupts several social cognitive abilities, including the theory of mind (ToM) and facial emotion recognition (FER). It unclear how specific ToM subcomponents, affective ToM, are affected in patients with MS abilities subtypes.MethodsA search PubMed, Web Science, Embase databases was conducted until June 2020. E...