The number of cases of envenomation by scorpions has grown significantly in Brazil since 2007, with the most severe cases being caused by the Tityus serrulatus scorpion. Although envenomed patients mostly suffer neurotoxic manifestations, other symptoms, such as hypertension, cannot be exclusively attributed to neurotoxins. Omics analyses have detected plentiful amounts of metalloproteases in T...

scorpion venoms contain of variety of peptides toxic to mammals ، insects and crustaceans. toxic peptides are the main factors in scorpion venom causing toxicity, (their amount being 1-3%of total venom.). most of the scorpion toxins have been isolated from the venoms of scorpions in the family buthidae. the scorpion buthotus schach belonging to the buthidae family is widely found in the western...

The present study was conducted to explore the following hypotheses: (i) do scorpions (the Egyptian scorpion Scorpio maurus palmatus) from different geographical locations exhibit intraspecific diversity in their venom? (ii) if so, is the variation associated with ecological or genetic factors, geographical distance, and/or multiple interrelated factors? and (iii) do the different toxins produc...

1 Rahav G, Weiss AT. Scorpion sting-induced pulmonary edema: scintigraphic evidence of cardiac dysfunction. Chest 1990; 97:1478-80 2 Gueron M. Actinomyces me rii breast abscess [letterl. Am J Med 1988; 84:369 3 Sofer S, Gueron M. Respiratory failure in children following envenomation by the scorpion L, iurus quinquestriatus: hemodynamic and neurological aspects. Toxicon 1988; 26:931-39 4 Gueron...

The intense pain induced by scorpion sting is a frequent clinical manifestation. To date, there is no established protocol with significant efficacy to alleviate the pain induced by scorpion envenomation. One of the important reasons is that, little information on pain-inducing compound from scorpion venoms is available. Here, a pain-inducing peptide (BmP01) has been identified and characterize...

Scorpions use their venom in defensive situations as well as for subduing prey. Since some species of scorpion use their venom more in defensive situations than others, this may have led to selection for differences in effectiveness in defensive situations. Here, we compared the LD50 of the venom of 10 species of scorpions on five different species of target organisms; two insects and three ver...

BACKGROUND Except for the northern region, where the Amazonian black scorpion, T. obscurus, represents the predominant and most medically relevant scorpion species, Tityus serrulatus, the Brazilian yellow scorpion, is widely distributed throughout Brazil, causing most envenoming and fatalities due to scorpion sting. In order to evaluate and compare the diversity of venom components of Tityus ob...