Introduction Oral leiomyomas are rare, benign neoplasms of smooth muscle origin, presenting as a solitary, asymptomatic, nodular mass. Case Presentation Here we present the case of a 54-year-old male with a lesion in the midline of his hard palate, which was diagnosed as a localized benign leiomyoma, along with a review of the recent literature. Discussion Diagnosis of a leiomyoma must be b...

BACKGROUND Pulmonary adenocarcinoma rarely spreads to the gynecologic tract, and has not been fully reported to metastasize within a leiomyoma. CASE A 47 year-old woman with recurrent pulmonary adenocarcinoma was incidentally found to have a positron emission tomography (PET) avid pelvic mass at the time of restaging. She was also noted to be anemic, and reported significant vaginal bleeding....

INTRODUCTION Primary leiomyoma of the lung is a rare benign tumor that usually presents as a solitary lesion predominantly in young females. Fewer than 100 cases have been reported. Common symptoms include fever, chronic cough, hemoptysis, chest pain, shortness of breath, and pneumonias. CASE PRESENTATION A 34-year-old, non-smoker female who presented with recurrent pneumonias. She was found ...

BACKGROUND Progesterone, via its nuclear receptor (PR), exerts an overall tumorigenic effect on both uterine fibroid (leiomyoma) and breast cancer tissues, whereas the antiprogestin RU486 inhibits growth of these tissues through an unknown mechanism. Here, we determined the interaction between common or cell-specific genome-wide binding sites of PR and mRNA expression in RU486-treated uterine l...

BACKGROUND Insulin-like growth factor-I (IGF-I) plays crucial roles in uterine leiomyoma cell growth through stimulating proliferation and inhibiting apoptosis. The present study was conducted to elucidate whether progesterone affects IGF-I and its receptor expression in cultured leiomyoma cells. METHODS Isolated leiomyoma cells were subcultured in Phenol Red-free Dulbecco's modified Eagle's ...

Introduction: The leiomyoma of the urethra is rare. It a benign mesenchymal tumor that affects smooth muscle urethra. These tumors often occur in women childbearing age middle their appearance about 41 years old. Case report: Here we report case 37 old white woman with progressive dysuria nodule sensation vagina Conclusions: Leiomyoma tumor, common uterus but very rare His diagnosis rarely ment...

The G-protein-coupled estrogen receptor (GPR30, GPER-1) is a member of the G-protein-coupled receptor 1 family and is expressed significantly in uterine leiomyomas. To understand the relationship between GPR30 single nucleotide polymorphisms and the risk of leiomyoma, we measured the follicle-stimulating hormone (FSH) and estradiol (E2) levels of 78 perimenopausal healthy women and 111 perimeno...

Rationale: Reports on perianal atypical leiomyoma, a perianal tumor, are rare. We confirmed a perianal atypical leiomyoma by its clinical presentation, magnetic resonance imaging findings, and immunohistochemistry. Patientconcerns:A 28-year-old female with a perianal mass found more than 4 years ago. The 5cm_4cm_4cm sized mass was located on the left side of the anus and vagina; The magnetic re...

Mesenchymal tumor of the esophagus is rare, and the most common mesenchymal tumor of the esophagus is leiomyoma [1-3]. The incidence of esophageal leiomyoma from autopsy cases ranges from 0.005 to 5% [2, 3]. Although detailed histopathological examination of autopsy and surgically resected case series demonstrated that its incidence is higher at 7.9% [1]. This disease is typically found in pati...

OBJECTIVE To examine urinary retention as an underreported complication of uterine leiomyoma. Reproductive-aged women with uterine leiomyoma often describe pelvic pressure and menorrhagia, however few complain of complete urinary retention. STUDY DESIGN We dis-cuss the cases of 8 women who presented to our emergency room with acute urinary retention over a 4-year period. RESULTS Patients ha...