Question What is the effectiveness of the levonorgestrel-releasing intrauterine system (IUS) compared with hysterectomy for the management of women with menorrhagia? Design: Randomised controlled trial, double-blind. Setting: Five university hospitals in Finland. Patients: Premenopausal women aged 35–49 years, with menorrhagia and no major gynaecological abnormalities were recruited to the stud...

INTRODUCTION Oculocutaneous albinism (OCA) in combination with a platelet function defect caused by a disturbed release reaction from platelet δ-granules (storage pool defect - SPD) is typical for the autosomal recessive inherited Hermansky-Pudlak syndrome (HPS). CASE REPORT A girl (age: 13 years) with OCA was hospitalized with transfusion-requiring menorrhagia. The suspicion of HPS was confi...

Up to 14 percent of women experience irregular or excessively heavy menstrual bleeding. This abnormal uterine bleeding generally can be divided into anovulatory and ovulatory patterns. Chronic anovulation can lead to irregular bleeding, prolonged unopposed estrogen stimulation of the endometrium, and increased risk of endometrial cancer. Causes include polycystic ovary syndrome, uncontrolled di...

BACKGROUND To study the Incidence of endometrial hyperplasia in perimenupausal women presenting with polymenorrhagia/menorrhagia. This observational study was conducted at Gynae 'B' unit of Khyber Teaching Hospital Peshawar from January 2000 to December 2001. METHODS One hundred consecutive patients who presented at Gynaecology OPD with Polymenorrhagia/ Menorrhagia were registered and inciden...

Abnormal uterine bleeding, the most common symptom of gynecological disease, is defined as menorrhagia or metrorrhagia. The former term applies only to an excessive loss of blood during the menstrual period. This loss may be evidenced in one of several ways: by an excessive menstrual flow, by a prolongation of the flow beyond the usual time limits, by a too frequent recurrence of the flow, or b...

This study has shown that, in women with menorrhagia, there were no statistically significant differences between IUS and hysterectomy for the outcomes of quality of life and psychological wellbeing. The quality-of-life data show that the IUS scored as well at 12 months as hysterectomy in seven of the eight areas assessed, with the only difference between the groups being pain scores, despite a...

Menorrhagia is a common presentation of bleeding disorders, especially vWD in women. The frequency of these disorders in women with menstruation problems is determined in this study. Total of 273 patients in reproductive age with menorrhagia were investigated for bleeding disorders in two steps. Step one includes CBC, PT, PTT and BT tests which were performed for all patients; patients diagnose...

OBJECTIVE To evaluate fibroid uterine volume reduction, symptom relief, and patient satisfaction with uterine artery embolization (UAE) for symptomatic fibroids. DESIGN Multicenter, prospective, single-arm clinical treatment trial. SETTING Eight Ontario university and community hospitals. Five hundred thirty-eight patients undergoing bilateral UAE. INTERVENTION(S) Bilateral UAE performed ...