E. coli is the most common Gram-negative bacteria causing neonatal meningitis, and E. coli meningitis continues to be an important cause of mortality and morbidity throughout the world. Recent reports of E. coli meningitis caused by antimicrobial resistant strains are a particular concern. These findings indicate that a novel strategy is needed to identify new targets for prevention and therapy...

Molar-incisor malformation (MIM) or molar root-incisor (MRIM) is a dental anomaly that affects teeth and maxillary central incisors. Even though, the etiology not exactly known, it has been reported several factors such as staphylococcal infection in neonatal period, neurological diseases meningitis hydrocephalus, ongoing medications, infectious premature delivery were effective. In this case r...

Sixty-three Escherichia coli strains isolated from neonatal sepsis or meningitis were studied and compared with previous data on fecal or urinary pyelonephritis-associated isolates from children. Characteristics significantly associated with neonatal infection were capsular type K1 (54%), O group 18 (27%), rough-type lipopolysaccharide together with K1 capsule (19%), and S fimbriae (29%). Withi...

The usefulness of CRP in early detection of neonatal septicemia/meningitis and urinary tract infection was studied in a neonatal unit using a semiquantitative latex-agglutination as a rapid screening method, and electroimmuno assay as reference method for CRP determination. In 94% of non-infected infants CRP was less than or equal to 15 mg/l and 82% had CRP less than 10 mg/l up to 3 days of age...

Cronobacter sakazakii (C. sakazakii), formerly Enterobacter sakazakii, is an emerging pathogen associated with the ingestion of contaminated reconstituted formula that causes serious illnesses such as bacteremia, septicemia, necrotizing enterocolitis, meningitis and death in low-birth-weight preterm neonatal infants. The objective of this study was to develop an animal model for human neonatal ...

Objectives: Infections in infants<90 days old are the leading cause of morbidity and hospitalization in neonatal practice. The etiological agents of sepsis (with or without meningitis) in Saudi neonates <90 days old are vastly undercharacterized. The aim of this study was to determine the bacterial etiology of neonatal sepsis and meningitis in these infants. Materials and methods: This retrospe...

Correspondence When to do a lumbar puncture in a neonate Sir, We enjoyed Dr Halliday's annotation on neonatal lumbar puncture but felt that his discussion of the role of lumbar puncture in suspected sepsis left an unfortunate question mark hanging over this procedure.' It is important we feel to distinguish between early onset and late onset sepsis. In early onset sepsis the usual route of infe...

Most serious neonatal streptococcal infections are caused by group-B streptococci. The pattern of serious group-B neonatal disease in Britain resembles that described in other countries; both "early-onset" and "late-onset" forms are seen, but reliable incidence rates have not yet been determined. Serological-type III strains predominate in neonatal meningitis in Britain, but not so markedly as ...

BACKGROUND Early onset sepsis remains a major cause for neonatal morbidity and mortality. OBJECTIVES The aim of this study was to describe and compare the clinical and laboratory characteristics of neonates in neonatal intensive care unit with culture positive and negative early onset sepsis and verify if there were any differences between the groups. METHODS A one year comparative prospect...

Three cases of neonatal meningitis, two of which were fatal, occurred in a premature baby unit during a period of one week. A fourth case occurred in the same unit six months later. Citrobacter koseri was isolated from the cerebrospinal fluid of all four cases. Detailed biochemical and serological examination of the organisms showed that two distinct bioserotypes were involved.