Regional Hospital Pardubice, Department of Dermatology, Czech Republic Regional Hospital Pardubice, Department of Clinical Microbiology, Czech Republic Charles University in Prague, Faculty of Science, Department of Botany, Benátska 2, 128 01 Praha 2, Czech Republic; [email protected] Charles University in Prague, First Faculty of Medicine, Dermatological Clinic, Czech Republic *corresponding...

Pigmented and non-pigmented nail alterations are a frequent challenge for dermatologists. A profound knowledge of clinical and dermatoscopic features of nail disorders is crucial because a range of differential diagnoses and even potentially life-threatening diseases are possible underlying causes. Nail matrix melanocytes of unaffected individuals are in a dormant state, and, therefore, fingern...

INTRODUCTION Chronic hemodialysis patients experience frequent and varied mucocutaneous manifestations in addition to hair and nail disorders. The aim of this study was to evaluate the prevalence of dermatological changes among patients with end-stage renal disease under hemodialysis in a hemodialysis unit in Tanta University hospitals over a period of 6 months, and to evaluate the relations of...

To cite: Bansal M, Mahajan S, Sankhwar S, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2015210902 DESCRIPTION A 30-year-old man born of a non-consanguineous marriage presented with asymptomatic peeling of skin throughout his body, sparing palms and soles, since birth. There was no preceding history of redness or fluid-filled lesions over the affected are...

TOPIC: Pulmonary Manifestations of Systemic Disease TYPE: Fellow Case Reports INTRODUCTION: Hydroxyurea is an antimetabolite that acts by inhibiting synthesis DNA. In addition to cancer therapy, it also used treat sickle cell anemia. However, daily use hydroxyurea not without risk, and one the lesser-known side-effects discoloration nails--specifically melanonychia (brown lines) blue lunula (na...

superficial dermis with occasional melanophages (Figure 3). The patient continued to receive cycles of chemotherapy, with no observed increase in pigmentation, until completing the treatment after 11 infusions. Five months after the last cycle of chemotherapy and 8 months after the appearance of the hyperpigmentation, no pigmentation was seen on the palms of the hands, and the reticular pigment...