Early detection of melanoma is a vital determinant in achieving favorable prognosis and patient outcomes which led to innovations skin imaging modalities that improved the diagnostic accuracy early melanoma. Studies reported cancer its stages using dermoscopy reflectance confocal microscopy, however there are limited reports detecting micro-melanomas less than 2-mm diameter. Previously, smalles...

OBJECTIVES Fine-needle aspiration cytology serves as a rapid and cost-effective tool for the diagnosis of melanoma, especially in the recurrent and metastatic cases. The diagnosis poses a challenge due to the varied morphological patterns. Spindle cell melanoma mimics other sarcomas and carcinomas on morphology. This study highlights the cytomorphological features of spindle cell melanoma and c...

Melanoma accounts for the majority of skin cancer deaths worldwide and has dramatically increased in incidence over the past half-century. Despite recent trends showing improved survival, and stabilization of incidence rates in younger Americans, melanoma incidence and mortality continue to rise unabated in older individuals, particularly in men over age 65. Efforts at early clinical detection ...

Acro-lentiginous melanoma, a pigmented lesion of the extremities, especially palms and soles, is defined by malignant tumor proliferation with high metastatic potential, which develops at expense melanocytes. Its incidence constantly increasing varies according to country ethnicity. diagnosis primarily histopathological, its management remains multidisciplinary, where surgery plastic surgeon oc...

Early detection and excision is the only effective treatment for malignant melanoma. To assess the effect of a consultant-delivered, rapid-access pigmented lesion clinic (PLC) established at the South Infirmary-Victoria University Hospital (SIVUH), we analyzed melanoma tumour-stage prior to (1998-2002) and after (2003-2007) the advent of the PLC. Patients attending SIVUH had a greater proportio...

IMPORTANCE The risk of next melanoma in patients with 2 or more previous melanomas stratified by familial and sporadic cases separately has not yet been reported, although a few population-based studies have assessed the risk of second melanoma. OBJECTIVE To assess the risk of next melanoma in patients with multiple primary melanomas by number of previous melanomas, stratified by demographic ...

BACKGROUND The incidence of melanoma is increasing worldwide. Guidelines for clinical skin exam for improving early diagnosis of melanoma remain inconsistent, and current data on factors associated with regular skin screening on a population basis are limited. METHODS We used self-reported data from 50,044 members of the California Twin Program, a population-based cohort of twins born in Cali...

Primary malignant melanoma of uterine cervix is extremely rare malignancy with very few case published reports. This neoplasm is having poor prognosis, so early diagnosis, staging and treatment is of extreme importance. 18F-FDG PET-CT (18F-labeled fluoro-2-deoxyglucose positron emission computed tomography) scan is an established modality to determine exact extent of disea...

Primary ovarian melanoma arising on a mature ovarian cystic teratoma is extremely rare. As best of our knowledge, to date, 49 cases have been reported in literature. Few information was reported about best management and therapy. We present a case occurred in a 69-year-old woman, without symptoms, who come to our unit for stress incontinence. A pelvic mass was detected and, after imaging evalua...