OBJECTIVES The aim of the study reported here was to assess the efficacy of an artificial tear emulsion for the treatment of dry eye associated with meibomian gland dysfunction (MGD). METHODS At five clinics, patients completed a 1-week treatment with their habitual topical therapy and then a 4-week treatment with open-label study medication: Systane® Balance Lubricant Eye Drops (Alcon, Alcon...

PURPOSE Lubricin is a principal boundary lubricating and anti-adhesion protein found in synovial fluid and several musculoskeletal tissues. This study investigates the presence of lubricin in the meibomian gland, lacrimal gland and ocular surface of healthy rabbits; prompted by the hypothesis that lubricin acts as boundary lubricant and anti-adhesive protein in the eye. METHODS Thirty six eye...

which either decreases tear production or increases tear evaporation (Figure 1). Increased tear osmolarity is the link between changes in the lacrimal glands and lids, and disease of the ocular surface. Studies of pre-clinical models of lacrimal gland disease and meibomian gland dysfunction show that the ocular surface changes of dry eye disease are dependent upon and proportional to increases ...

The Intense Pulsed Light (IPL) may be used for the treatment of acne, photoepilation, photorejuvenation and more recently their use has been advocated for treatment of meibomian gland dysfunction and dry eye. For the treatment of dysfunction of the meibomian gland, Intense Pulsed Light was used with the same acne treatment settings in the scenario Fitzpatrick type 1, fluent between 8 and 12 J/c...