REASON FOR PERFORMING STUDY Using an adjustable heart bar shoe model of foot pain, the objective of this study was to test the hypothesis that the combined use of phenylbutazone (PBZ) and flunixin meglumine (FM) would prove more efficacious in alleviating lameness than either drug alone. MATERIALS AND METHODS One hour after induction of lameness at weekly intervals, 8 healthy adult Thoroughbr...

BACKGROUND Leishmaniasis has been identified as a major public health problem in tropical and sub-tropical countries. The present study was aimed to investigate antileishmanial effects of various extracts of Berberis vulgaris also its active compoenent, berberine against Leishmania tropica and L. infantum species on in vitro experiments. METHODS In this study in vitro antileishmanial activity...

BACKGROUND Therapeutic response in infectious disease involves host as well as microbial determinants. Because the immune and inflammatory response to Leishmania (Viannia) species defines the outcome of infection and efficacy of treatment, immunomodulation is considered a promising therapeutic strategy. However, since Leishmania infection and antileishmanial drugs can themselves modulate drug t...

Aim: To see the efficacy of meglumine antimoniate alone in comparison with combination and CO2 ablative laser among patients cutaneous leishmaniasis. Study design: Quasi-experimental study. Place duration study: Department Dermatology, Pakistan Emirates Military Hospital, Rawalpindi from 9th July 2020 to 8th January 2021. Methodology: Sixty (30 each group) diagnosed cases leishmaniasis by skin ...

BACKGROUND & OBJECTIVES Pentavalent antimony compounds are the first line of drugs in the treatment of cutaneous leishmaniasis. However, because of their potential toxic effects, many investigations are performed to find an effective and safe treatment for cutaneous leishmaniasis patients. Our objective in this investigation was to compare the effect of oral omeprazole and low dose systemic meg...

Objective: To study the clinical efficacy of meglumine adenosine cyclophosphate combined with perindopril in treating patients with chronic heart failure. Methods: Three hundred and twelve patients with chronic heart failure were enrolled and divided evenly into an observation group and a control group according to treatment methods, one hundred and fifty-six patients in each group. Patients in...

GENERIC NAME PAGE Amodiaquine 614 Atovaquone 616 Chloroguanide 615 Chloroquine 613 Dapsone 615 Diloxanide 609 Eflornithine 610 Hydroxychloroquine 614 Iodoquinol 608 Mefloquine 616 Meglumine antimonate 611 Melarsoprol 610 GENERIC NAME PAGE Metronidazole 608 Nifurtimox 610 Paromomycin 609 Pentamidine 609 Primaquine 614 Pyrimethamine 614 Quinine 615 Sodium stibogluconate 611 Suramin 609 Trimethopr...

The economic consequences of bovine respiratory disease (BRD) in weaned calves and stocker cattle are considerable in terms of loss from death, decreased growth performance, increased medication costs, and labor. It is a complex disease involving both viruses and bacteria. The inflammation that accompanies BRD can result in permanent lung damage. The goals of therapeutic treatment for BRD are t...

BACKGROUND & OBJECTIVES Association between polymorphisms in the natural resistance associated macrophage protein 1 (NRAMP1) gene and susceptibility to cutaneous leishmaniasis (CL) has been demonstrated worldwide; however, the reported results were inconsistent. This study aimed to determine the association of NRAMP1 variants with susceptibility to CL infection and patients' response to treatme...