Introduction: Peripheral nerve injury leads to neuropathic pain syndromes and different sensation like allodynia and hyperalgesia. Different animal models of neuropathic pain are used to study the neuropathic pain mechanisms. The present study was performed on two models, (SNI). The purpose of this study was comparing the behavioral responses of yhese two models and the role of saphenous and...

signal regulatory proteins (sirp) belong to immunoglobulin super family (igsf) and relate to integrin signaling cascades. it has been shown that sirpa is expressed in a variety of cells including myeloid cells and neurons. in the present study the expression of this igsf member in articular chondrocytes was investigated. methods: using a panel of anti-sirpalpha antibodies, immunohistochemistry,...

Mechano-Bactericidal In article number 2213650, Joonseok Lee and co-workers develop a puncturable nanostructured air filter via catalyst droplet-based synthesis to effectively collect deactivate airborne bacteria. The unique nanostructures featuring nano-edge can cause mechanical damage the bioaerosol without external stimulations, resulting in inhibition of bacterial proliferation.

Key points C-nociceptors are generally assumed to have a low maximum discharge frequency of 10–30 Hz. However, only mechano-insensitive ‘silent’ cannot follow electrical stimulation at 5 Hz (75 pulses) whereas polymodal in the pig up 100 without conduction failure. Sensitization by nerve growth factor increases following nociceptors skin and might thereby contribute particular intense pain sens...