Galectin-3 is a carbohydrate-binding lectin, which has been implicated in the modulation of atherosclerotic pathophysiology, and is highly expressed in monocytes, macrophages and endothelial cells within atherosclerotic plaques. Modified citrus pectin (MCP) is produced from citrus pectin via pH and temperature modifications, which break it into shorter, non‑branched, galactose‑rich carbohydrate...

The optimal 1-methylcyclopropene (1-MCP) treatment to slow ripening of whole "Keitt" mangos, either alone or in combination with hot water treatment (HWT) (prior to or post 1-MCP) was identified. USDA-APHIS mandates that HWT can be used for control of fruit flies, but this may affect fruit response to 1-MCP. Mangos were evaluated by repeated measurement of nondestructive firmness, peel color, a...

Inflammation plays a pathogenic role in the development of restenosis after percutaneous transluminal coronary angioplasty (PTCA). Monocyte chemoattractant protein-1 (MCP-1) is a potent chemoattractant of monocytes; however, its role in the pathophysiology of restenosis is still unclear. We set out to investigate the role of MCP-1 in restenosis after PTCA. In addition, we tested the hypothesis ...

The complex α-[Fe(mcp)(OTf)2] (mcp = N,N′-dimethyl-N,N′-bis(pyridin-2-ylmethyl)-cyclohexane-1,2-diamine and OTf trifluoromethanesulfonate anion) was reported in 2011 by some of us as an active wa...

This presentation focuses primarily on recent developments in new technologies that have impacts on decay control. These technologies include 1-methylcyclopropene (1-MCP) and new preand postharvest fungicides. With the increasing use of 1-MCP in the apple industry, depending on varieties, many apples do not have to be drenched with diphenylamine (DPA) prior to storage. Because use of 1-MCP has ...

We present initial characterization data from a new single line of sight (SLOS) x-ray framing camera. The instrument uses an image dissecting structure inside an electron optic tube to produce up to four simultaneous DC images from a single image incident on the cathode and a microchannel plate based device to provide the temporal gating of those images. A series of gated images have been obtai...

Traditionally, the process capability index is developed assuming that the process output data are independent and follow normal distribution. However, in most environmental cases, the process data have more than one quality characteristic and exhibit property of autocorrelation. We propose two novel multivariate process capability indices for autocorrelated data, NMACp and NMACpm for the-nomin...

Chemokines, including MCP-1, are crucial to mounting an effective immune response due to their ability to recruit other immune cells. We show that sustained LPS or poly(I:C)-stimulated MCP-1 production requires an IFNβ-mediated feedback loop. Consistent with this, exogenous IFNβ was able to induce MCP-1 transcription in the absence of other stimuli. Blocking IFNβ signaling with Ruxolitinib, a J...

BACKGROUND AND PURPOSE We have previously demonstrated that the local delivery of monocyte chemotactic protein-1 (MCP-1) via an MCP-1-releasing poly(lactic-co-glycolic acid)-coated coil promotes intra-aneurysmal tissue healing. In this study, we demonstrate that interleukin-6 (IL-6) and osteopontin are downstream mediators in the MCP-1-mediated aneurysm-healing pathway. METHODS Murine carotid...

Chemokines are chemotactic cytokines that play an important role in recruiting leukocytes in allergic inflammation. Monocyte chemoacctractant protein (MCP)-4 is a CC chemokine with potent chemotactic activities for eosinophils, monocytes, T lymphocytes, and basophils and therefore represents a good candidate to participate in allergic reactions. To determine if MCP-4 plays a role in asthma, we ...