Blood neutrophil counts are determined by the differentiation and proliferation of precursor cells, the release of mature neutrophils from the bone marrow, margination, trafficking and transmigration through the endothelial lining, neutrophil apoptosis, and uptake by phagocytes. This brief review summarizes the regulation of blood neutrophil counts, which is in part controlled by G-CSF, IL-17, ...

Fig. 1. (A) Peripheral blood smear showing mature lymphocytes with dense chromatin, no nucleoli, and scanty agranular cytoplasm (Wright-Giemsa stain, ×1,000). (B) Bone marrow lymphocytosis on aspirate (Wright-Giemsa stain, ×1,000). toplasmosis diagnosed on bone marrow aspirate cytology: report of four cases. East Afr Med J 2009;86(Suppl 12):S102-5. 3. Caldwell CW, Taylor H. Visualization of his...

Abstract Although multiple studies have investigated the mesenchymal stem and progenitor cells (MSCs) that give rise to mature bone marrow, high heterogeneity in their morphologies properties causes difficulties molecular separation of distinct populations. In this study, by taking advantage resolution single cell transcriptome, we analyzed Sca-1 PDGFR-? fraction mouse marrow tissue. The transc...

Segmental bone allografts are widely used in managing large cortical defects. To improve host-graft union, the effect of allograft on a tibial defect augmented with non-vascularized periosteal flap was studied. Twelve mature Australian white rabbits (Oryctolagus cuniculus) were divided into intervention groups and control group. Bone defects treated segmental wrapped flap. The group transplanta...

The aim: to conduct a comparative study of osteoreparative regeneration, namely in the periosteal and intermediate areas cortex, during intramedullary osteosynthesis femur rats with without reaming bone marrow canal.
 Materials methods. work is based on results an experimental conducted 56 white mature laboratory rats, which simulated diaphyseal fracture performed stable nail canal first s...

blood cell lineage which still contain a nucleus; they are also known as erythroblasts or – obsolete – normoblasts. In healthy adults and older children, NRBC can only be found in blood-building bone marrow where they mature. Their appearance in peripheral blood points to extramedullary erythropoiesis (outside the bone marrow) or disruption of the blood – bone marrow barrier. Both possible scen...

INTRODUCTION The purpose of this study was to determine how the amount of surgical insult affects the quantity and maturity of dentoalveolar bone around teeth that have been orthodontically moved. METHODS A split-mouth design with 8 foxhound dogs was used to evaluate bone surrounding maxillary second premolars that were protracted for 15 days and retained for 7 weeks. The maxillary first prem...

Metastatic breast cancer shows extreme tropism for the bone microenvironment, leading to the establishment of osteolytic metastases. Perpetuation of tumor-induced osteolysis requires a continuous supply of osteoclast precursors migrating into the bone microenvironment that can subsequently differentiate into mature osteoclasts and resorb bone. Thus, identification and subsequent targeting of ch...

Endometrial osseous metaplasia is a rare pathological condition with mature bone in the endometrium and can be a cause for menorrhagia and infertility as bone in the endometrium acts like intrauterine contraceptive device. We report one such case with brief review of literature in a 28-year-old woman presenting with history of menorrhagia.

The contribution of the tumor stroma to cancer progression has been increasingly recognized. We had previously shown that in human neuroblastoma tumors orthotopically implanted in immunodeficient mice, stromal-derived matrix metalloproteinase-9 (MMP-9) contributes to the formation of a mature vasculature by promoting pericyte recruitment along endothelial cells. Here we show that MMP-9 is predo...