Although the adverse effects of maternal aging on reproductive outcomes have been investigated widely, there is no consensus on the impact of paternal age. Therefore, we investigated the effect of paternal age on reproductive outcomes in a retrospective analysis of 9,991 in vitro fertilization (IVF) cycles performed at the Reproductive Medicine Center of the Third Affiliated Hospital of Guangzh...

Advanced maternal age defined as age 35 years or more at estimated date of delivery is considered to have higher incidence of obstetric complications and adverse pregnancy outcome than younger women. The objective of this study was to compare the obstetric and perinatal outcome of pregnancies in women with advanced maternal age > or = 35 years with that of younger women < 35 years. A prospectiv...

To assess the effect of maternal age on obstetric intervention and pregnancy outcome, a retrospective study compared obstetric intervention, pregnancy complications and outcome in 73 women of age > 35 years with 471 women of age 20-25 years attending Prince Ali Military Hospital, Jordan from June 1999 to May 2000. Older women were found to have significantly higher rates of medical complication...

OBJECTIVE To investigate the impact of advanced maternal age on the rate of perinatal mortality. DESIGN Retrospective cohort study including all 56,517 singleton hospital deliveries between 1999 and 2008. METHODS Data were analyzed according to maternal age at delivery in 3 groups of women, 25-34 years, 35-39 years and ≥ 40 years, using the youngest as the reference group. RESULTS Odds ra...

this study examines the association of father's and mother's age with the severity of inattention and hyperactivity/impulsivity. participants are 470 children with attention deficit hyperactivity disorder (adhd) diagnosed according to dsm-iv diagnostic criteria. moreover, parents reported the severity of adhd symptoms through completing adhd checklist. mother's and father's age was associated w...

Nucleotide-binding domain and leucine-rich repeat (NLR) proteins are well-known for their key roles in the immune system. Ectopically expressed NLRP2 in immortalized cell lines assembles an inflammasome and inhibits activation of the proinflammatory transcription factor NF-κB, but the physiological roles of NLRP2 are unknown. Here, we show that Nlrp2-deficient mice were born with expected Mende...

Mothers and newborns in Canada are supported by programs that address their needs from pre-conception to the perinatal period and beyond. Often, these programs target one or more at-risk groups of mothers: those with pre-existing health conditions such as diabetes, hypertension or mental health concerns; women with unhealthy pre-pregnancy weights; Aboriginal women; or women of an age outside th...

OBJECTIVE To examine the effect of maternal age on incidence of nonchromosomal fetal malformations. METHODS Malformations detected at birth or in the newborn nursery were catalogued prospectively for 102,728 pregnancies, including abortions, stillbirths, and live births, from January 1, 1988 to December 31, 1994. Maternal age was divided into seven epochs. Relative risks (RRs) were used to co...

A group of patients (150) suffering from keratoconus were asked their mother's age at their birth. A statistically significant excess of older mothers as compared with the general population was found. The social class of the patients was found to have a distribution different from the general population, and it is suggested that this is related to the patient's maternal age.

OBJECTIVE To estimate the effect of maternal age on obstetric outcomes. METHODS A prospective database from a multicenter investigation of singletons, the FASTER trial, was studied. Subjects were divided into 3 age groups: 1) less than 35 years, 2) 35-39 years, and 3) 40 years and older. Multivariable logistic regression analysis was used to assess the effect of age on outcomes after adjustin...