DNA technologies have revolutionalized modern science in many ways. DNA (Deoxyribonucleic acid), the hereditary material in all living organism from bacteria to bull, controls and directs all the functions of a living organism. Many techniques have been evolved to understand and manipulate the DNA for many purposes like parentage analysis, curing genetic diseases, forensics, gene therapy and to...

Perspectives on whether the functions of MAS, a G protein-coupled receptor, are beneficial or deleterious in the heart remain controversial. MAS gene knockout reduces coronary vasodilatation leading to ischemic injury. G protein signaling activated by MAS has been implicated in progression of adaptive cardiac hypertrophy to heart failure and fibrosis. In the present study, we observed increased...

MAS MT is a myotropic decapeptide isolated from Manduca sexta. This peptide exerts stimulatory effect on insects heart-beat frequency. The present study was undertaken in order to determine a probable antinociceptive effect in rats of native synthetic decapeptide, MAS MT-I and its two analogs, heptapeptides MAS MT-II and MAS MT-III. All these peptides were applied directly into the lateral brai...

Cytoplasmic genic male sterility (CGMS) is a system that uses the maternal line for hybrid production, ensuring no obscurity of F1 seed purity and reducing cost production. Identification gene important plant improvement classification when using molecular marker-assisted selection (MAS) method. This study aimed to produce new (A-line) its maintainer (B-line) by transferring male-sterile from a...

BackgroundCytokine storm syndromes are life-threatening complications that can occur in children with rheumatic conditions (macrophage activation syndrome [MAS]), inherited cytotoxicity defects (ie, primary haemophagocytic lymphohistiocytosis [HLH]), or as a result of infection malignancies secondary HLH). To adequately steer treatment, an early and clear discrimination these entities is essent...

The functions and signalling mechanisms of the Ang-(1-7) [angiotensin-(1-7)] receptor Mas have been studied extensively. However, less attention has been paid to the intracellular regulation of Mas protein. In the present study, PSD95 (postsynaptic density 95), a novel binding protein of Mas receptor, was identified, and their association was characterized further. Mas specifically interacts wi...

BACKGROUND Macrophage activation syndrome (MAS) is the secondary hemophagocytic lymphohistiocytosis associated with rheumatic diseases. Recently, the different cytokine profiles between systemic juvenile idiopathic arthritis (sJIA)-associated MAS (sJIA-MAS) and juvenile systemic lupus erythematosus (JSLE)-associated MAS (JSLE-MAS) were reported. However, there is little information about juveni...

Background: This study has focussed on identifying the Simple Sequence Repeat (SSR) markers associated with sucking pests (more precisely jassid) tolerance/resistance loci. The was initiated 4348 mapped SSR to differentiate between resistant (R-1) and susceptible (BS-1) genotypes. Out of (retrieved from cotton microsatellite database cottongen.org) used,17 were showing polymorphism parental lin...

The extracellular matrix (ECM) of decellularized organs possesses the characteristics of the ideal tissue-engineering scaffold (i.e., histocompatibility, porosity, degradability, non-toxicity). We previously observed that the muscle acellular scaffold (MAS) is a pro-myogenic environment in vivo. In order to determine whether MAS, which is basically muscle ECM, behaves as a myogenic environment,...

Background: The purpose of this study was to find the accurate absorbed dose in the femur bone marrow during the X-ray radiography for constant mAs and AEC techniques. Materials and Methods: The DOSXYZnrc was used to simulate radiation doses in two human femurs during diagnostic radiography. EGSnrc phantoms produced from actual CT images of human femurs were modified by adding seven micrometre ...