ABSTRACT We analyzed the mechanisms underlying enhanced IgA production in cells of Peyer's patch via membrane vesicles derived from Lactobacillus sakei subsp. NBRC 15893. Depletion CD11c+ suppressed mediated by vesicles. Meanwhile, stimulation bone-marrow–derived dendritic with increased gene expression inducible nitric oxide synthase, retinaldehyde dehydrogenase 2, and several inflammatory cyt...

Background: Hematological disorders are found commonly in the general population existing on both ends of spectrum with minute like iron deficiency anemia to as severe bone marrow infiltration Objective: To assess frequency hematological malignancies based bone-marrow aspiration and trephine biopsy patients presenting tertiary care hospital Methodology: The current study was cross-section descr...

objective(s):to study the effect of low-frequency vibration on bone marrow stromal cell differentiation and potential bone repair in vivo. materials and methods:forty new zealand rabbits were randomly divided into five groups with eight rabbits in each group. for each group, bone defects were generated in the left humerus of four rabbits, and in the right humerus of the other four rabbits. to t...

background: finding a suitable method for rapid, accurate and reliable estimation of absorbed dose has high priority in management of the radiation exposed persons. shortly after radiation exposure, apoptosis is a major detriment in proliferative tissues such as the hematopoietic system. therefore, quantification of apoptosis in these tissues could be useful for rapid estimation of radiation ex...

bone marrow is a primary source of various kinds of blood cells and, thus, is frequently used for evaluation of therapeutic agents. the influence of physical regular training and curcumin supplementation on the cellularity of the femur bone marrow was investigated in rats exposed to lead acetate. 48 the wistar rats were randomly assigned to one of the six groups include; 1)base, 2)sham-operate,...

Objective(s): Functional imaging presents a non-invasive process that may capture the hyper-metabolic nature of red bone marrow in myeloproliferative neoplasms, such as polycythemia vera (PV). Methods: This study analyzed the FDG-PET/CT scans (n=12) of six patients diagnosed with PV and six age-sex matched controls using a quantitative global analysis methodol...

Blastic Plasmacytoid Dendritic Cell Neoplasia (BPDCN) is a rare hematological malignancy whose pathogenesis has not yet been elucidated. Skin, bone marrow, and lymph node involvement can be observed, it generally seen in men old adults. Immunohistochemistry (IHC) features of skin marrow biopsy are essential for diagnosis. There no standardized treatment options this malignancy, the prognosis pa...