Classical Marr-Albus theories of cerebellar learning employ only cortical sites of plasticity. However, tests of these theories using adaptive calibration of the vestibulo-ocular reflex (VOR) have indicated plasticity in both cerebellar cortex and the brainstem. To resolve this long-standing conflict, we attempted to identify the computational role of the brainstem site, by using an adaptive fi...

CouR, a MarR-type transcriptional repressor, regulates the cou genes, encoding p-hydroxycinnamate catabolism in the soil bacterium Rhodococcus jostii RHA1. The CouR dimer bound two molecules of the catabolite p-coumaroyl-CoA (Kd = 11 ± 1 μM). The presence of p-coumaroyl-CoA, but neither p-coumarate nor CoASH, abrogated CouR's binding to its operator DNA in vitro. The crystal structures of ligan...

Introduction to motor learning theory There have been successive attempts to understand the relationships between the structure, function, and dynamics in neuronal circuits (Arbib et al., 1998) in the hope of explaining behavior. At different times these attempts have been based on the available experimental data and conceptual tools and have been synthesized into various theories and models. O...

The Balanced Scorecard (BSC) is a very powerful and successful strategic performance management tool. This management white paper describes a BSC in simple terms. The paper outlines the four perspectives of a Balanced Scorecard and explains the importance of Strategy Maps. It shows how many organisations use the Balanced Scorecard today and describes the key benefits of a scorecard implementati...

One of the plantation commodities that has potential to become a source foreign exchange for Indonesia is cloves (Syzigium aromaticum L. Marr. and Perr.). National production fluctuates, so in it known as big harvest, medium harvest small harvest. The clove cigarette industry main consumer because absorbs 95% national which used raw material producing. This causes volume exported reduced, there...

• Comparisons of the models Marr, Ito and Albus for motor learning control. A review synaptic plasticity in achieving supervised learning. Condon theory may be relevant to newer functions cerebellum. Computational roles cerebellar internal models. Hierarchical reinforcement with multiple as a new computational Fifty years have passed since David Masao Ito, James proposed seminal functions. Thes...

OBJECTIVE To determine the effect of growth of five strains of Salmonella enterica and their isogenic multiply antibiotic-resistant (MAR) derivatives with a phenolic farm disinfectant or triclosan (biocides) upon the frequency of mutation to resistance to antibiotics or cyclohexane. METHODS Strains were grown in broth with or without the biocides and then spread on to agar containing ampicill...