Butenolides are a family of lactones containing double bond and have been frequently found in the extracts Streptomyces bacterial species with various pharmacological activities. In this study, seven butenolides (1–7) were discovered isolated from culture broth marine-derived sp. 13G036 based on molecular networking analysis. Among isolates, compound 7 was first as natural product study. The st...

Four new sesquiterpenoid naphthoquinones, marfuraquinocins A−D (1−4), and two new geranylated phenazines, phenaziterpenes A (5) and B (6), were isolated from the fermentation broth of Streptomyces niveus SCSIO 3406, which originated from a South China Sea sediment sample obtained from a depth of 3536 m. The structures of 1−6 were elucidated on the basis of extensive MS and one-dimensional and t...

Exploitation and overuse of antibiotics in the health sectors leads to the development of resistance mechanism in microbes against antibiotics. As a consequence, there is a vital need to develop effective lead compound from natural sources. Compounds derived from marine habitat have a remarkable nature of unique chemical structures and exhibit bioactivity, so it can be used in the treatment aga...

Screening of new insecticidal and acaricidal antibiotics was carried out with reference to anti-brine shrimp activity from actinomycete strains isolated from marine environments. Of 200 actinomycete isolates, one isolate was found to produce a new substance, altemicidin. The strain was isolated from sea mud collected at Gamo, Miyagi Prefecture, Japan, and identified as Streptomyces sioyaensis S...

Two new alkaloids, strepchazolins A (1) and B (2), together with a previously reported compound, streptazolin (3), were isolated from a marine actinomycete, Streptomyces chartreusis NA02069, collected in the Coast of Hainan Island, China. The structures of new compounds were determined by extensive NMR, mass spectroscopic and X-ray crystallographic analysis, as well as modified Mosher's method....