Mannan is a class of cell wall polysaccharides widespread in the plant kingdom. structure and properties vary according to species organ. The walls cereal grains have been extensively studied due their role processing beneficial effect on human health as dietary fiber. Recently, we showed that mannan wheat (Triticum aestivum) grain endosperm has linear β-1,4-linked mannose residues. aim this wo...

Mild alkaline degradation of Saccharomyces cerevisiae X2180 wild type mannan, under conditions that effect /3 elimination of the substituted serine and threonine residues, releases mannose, mannobiose, mannotriose, and mannotetraose. Methylation analysis demonstrated that these fragments have the same structures as those that are obtained by acetolysis of the polysaccharide component of the yea...

BACKGROUND To assess the performance of Candida albicans germ tube antibody (CAGTA), (1 → 3)-ß-D-glucan (BDG), mannan antigen (mannan-Ag), anti-mannan antibodies (mannan-Ab), and Candida DNA for diagnosing invasive candidiasis (IC) in ICU patients with severe abdominal conditions (SAC). METHODS A prospective study of 233 non-neutropenic patients with SAC on ICU admission and expected stay ≥ 7...

Purpose. To analyze the array of special literature and summarize information obtained on peculiarities prebiotics based mannan-oligosaccharides. review basic principles prospects their application in fish feeding, first all conditions aquaculture Ukraine. Findings. An overview modern scientific publications pecularitires mannan-oligosaccharides, prerequisites for widespread use is presented. T...

Antigen-presenting cells including dendritic cells (DCs) express mannan receptors (MR) on their surface, which can be exploited in cancer therapy by designing immune-stimulatory viruses coated with mannan-modified capsids that then bind to DCs and initiate a potent immune response. Although the combination of anti-angiogenesis and cancer immunotherapy agents has a synergistic antitumor effect, ...

The first automated solution-phase synthesis of β-1,4-mannuronate and β-1,4-mannan oligomers has been accomplished by using a β-directing C-5 carboxylate strategy. By utilizing fluorous-tag assisting purification after repeated reaction cycles, β-1,4-mannuronate was synthesized up to a hexasaccharide with limited loading of a glycosyl donor (up to 3.5 equiv) for each glycosylation cycle due to ...

BACKGROUND Mannan is one of the primary polysaccharides in hemicellulose and is widely distributed in plants. β-Mannosidase is an important constituent of the mannan-degrading enzyme system and it plays an important role in many industrial applications, such as food, feed and pulp/paper industries as well as the production of second generation bio-fuel. Therefore, the mannose-tolerant β-mannosi...

Two experiments were conducted to evaluate the effects of a commercial endo-β-D-mannanase (Hemicell) on overall performance, MEn, net energy for gain, and some serum parameters of broilers fed diets varying in β-mannan level (experiment 1) and to evaluate effects of enzyme level on the same variables in broilers fed diet high in β-mannan (experiment 2). As a semipurified β-mannan source, guar g...

Drug delivery researches has drawn tons of attention to achieve the targeted therapies that work for many diseases. Nanogels, a type polymeric hydrogels with nanoscale size, are promising materials drug applications. However, current polymers used synthesizing nanogels lack in biocompatibility, stability, and low biosafety. This review focus on mannan-based high loading capacity, multifunctiona...

The effect of 2-deoxy-d-glucose and cycloheximide on the synthesis and secretion of the cell-wall constituents protein and mannan in yeast protoplasts was examined in detail. Although the 2-deoxy-d-glucose hardly influenced protein synthesis, a significant parallel inhibition of carbohydrate and protein secretion into the medium was observed. The mechanism of this inhibition is considered as an...