Mucosa-associated lymphoid tissue (MALT) lymphomas are a distinct clinico-pathologic entity mainly associated with chromosomal translocations involving the MALT1 gene. Therefore, these chromosomal rearrangements have been traditionally used to identify tumor MALT lymphoma B-cells, and they have always been detected in differentiated tumoral B cells. However, the hematopoietic progenitor and ste...

A median 80 months follow-up with updated time to progression (TTP) and survival data is presented from a multicenter phase II trial using 2-Chlorodeoxyadenosine (2-CdA) in the treatment of extranodal marginal zone B-cell lymphoma of the mucosa-associated lymphoid tissue type (MALT lymphoma) [1]. With the exception of Helicobacter pylori (HP) eradication therapy in localized gastric disease no ...

Synchronous malignant mucosa associated lymphoid tissue MALT-lymphoma of the small bowel and adenocarcinoma of the colon in the same patient is a scarce rarity. Only few cases have been reported so far. Thus, it might be of interest to report such a case of coexisting malignant MALT-lymphoma of the duodenum and adenocarcinoma of the large bowel.

The group of marginal zone B-cell lymphomas (MZL) comprises three different entities, extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (currently called MALT lymphoma), nodal marginal zone B-cell lymphoma (previously known as monocytoid lymphoma), and splenic marginal zone B-cell lymphoma (with or without circulating villous lymphocytes).[1-3] Primary splenic and no...

BACKGROUND Low grade malignant lymphomas arising from mucosa associated lymphoid tissue (MALT) represent a distinct clinicopathological entity. The cytogenetic findings and molecular genetics of MALT lymphomas remain minimally defined. Cytogenetic studies infrequently constitute part of the diagnostic work-up of MALT lymphomas, most commonly due to small biopsy size and their extranodal localiz...

BACKGROUND Primary pulmonary mucosa-associated lymphoid tissue (MALT) lymphoma is a low-grade B cell lymphoma that is a type of non-Hodgkin lymphoma and a type of primary pulmonary malignant lymphoma. MALT lymphomas affecting the lung show various findings on chest computed tomography, which range from typical nodules or areas of consolidation to findings that are extremely rare in pulmonary MA...

Indolent lymphomas are a markedly heterogeneous group of lymphoproliferative disorders including B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma, lymphoplasmacytoid lymphoma, follicular lymphoma, mantle cell lymphoma and mucosa-associated lymphoid tissue (MALT) lymphoma. The molecular pathophysiology of indolent lymphoma is characterized by distinct genetic pathways which selecti...

BACKGROUND To present a case of conjunctival lymphoma in a young woman complicated by pregnancy. CASE PRESENTATION A 38-year-old previously healthy woman presented with a 2-year history of progressive right blepharoptosis. Giant papillomatous sessile masses were identified in the upper and lower fornix bilaterally and involved the tarsus of the right upper lid. The remaining ophthalmic examin...

fying endoscopy in the diagnosis of gas− tritis and gastric cancer has been report− ed [1, 2]. However, there have been no re− ports on magnified endoscopic images of nonepithelial gastric tumors. We con− ducted a long−term follow−up of gastric mucosa−associated lymphoid tissue (MALT) lymphoma by magnifying endos− copy. The magnifying electronic video endo− scope used was a GIF−Q240Z model (Oly...

Rectal mucosa-associated lymphoid tissue (MALT) lymphoma is a rare condition. Although the majority of patients undergo surgical resection, a definitive treatment for rectal MALT lymphoma has not yet been established. In the present study, we report the outcome of radiotherapy in 3 patients with rectal MALT lymphoma. Our cohort ranged from 56 to 65 years of age. The male/female ratio was 1:2, a...