Sarcomas are a heterogeneous group of malignant neoplasms arising from mesenchymal cells. They account for less than 1% of adult solid malignant cancers. The vast majority are soft tissue sarcomas, while malignant bone tumors represent only about 10% of them [1]. In fact, sarcomas comprise over 50 different histological subtypes; they may arise in stem cell-like population (primitive neuroectod...

Angiomyolipomas (AMLs) are a benign mesenchymal tumor that typically occurs in the kidney and very rare in the liver. Even though these tumors can be diagnosed with imaging tecniques, diagnosis mainly relies on pathological findings. Because AMLs can mimic other hepatic tumors such as hepatocellular carcinoma (HCC) on radiologic images due to some of the features. We presented a giant hepatic A...

Solitary fibrous pleural tumors are rare masses of mesenchymal origin that may be mistaken for mesothelioma. A positive staining of vimentin, negative staining of cytoplasmic keratin, and expression of the CD34 antigen can confirm the presence of a solitary fibrous pleural tumor. Although most tumors of this type are benign, they possess a malignant potential and thus should be excised. We repo...

background: thromboembolism is the most important complication of cancers.the aim of this study was to determine d-dimer levels in benign and malignant tumors of the uterus, ovary and cervix. subjects and methods: this was a cross sectional study and it was conducted on 90 female patients referred to imam khomeini and arash hospitals because of uterine, cervical and ovarian tumors in 2013-2014....

Benign liver tumors are common in general population, can be seen in 9% to 20% of individuals. Some of these tumors have a completely benign natural history and do not need to be resected, while others carry a risk of growth, hemorrhage, or malignant transformation and should be operatively removed. Obtaining a preoperative diagnosis is therefore critical, and this single factor remains the pri...

background and aims. mast cells are one of the characteristic factors in angiogenesis, growth, and metastatic spread of tumors. the distribution and significance of mast cells in many tumors have been demonstrated. however, few studies have evaluated mast cell infiltration in salivary gland tumors. in this study, mast cell counts were evaluated in benign and malignant salivary gland tumors. mat...

Phosphaturic mesenchymal tumor can cause osteomalacia due to excessive secretion of fibroblast growth factor 23 (FGF23), which disrupts the metabolism phosphate and vitamin D. These tumors are predominantly benign, but less than 5% them malignant forms. This article presents first clinical case in Russian Federation a 69-year-old patient with severe hypophosphatemia metastatic prostate cancer. ...

A schwannoma is a kind of neurogenic tumor that rarely occurs in the gastrointestinal tract. Gastric schwannomas make up 0.2% of all gastric neoplasms. Gastrointestinal stromal tumors (GIST) are the most common mesenchymal tumors and up to 60-70% of GIST occur in the stomach. Schwannoma and GIST are similar in clinical features, so they are difficult to differentiate preoperatively. Differentia...

BACKGROUND Cardiac tumors, especially malignant, are rare but aggressive tumors that mostly arise from the mesenchymal cells and represent a challenging diagnosis for clinicians. Recently, fluorine-18-fluorodiography positron emission tomography and computed tomography (F-FDG PET/CT) is an increasingly popular new technique with diagnosis of tumor. METHODS We report a case of a right heart tu...

Platelet-derived growth factor (PDGF) isoforms are important mitogens for different types of mesenchymal cells, which have important functions during the embryonal development and in the adult during wound healing and tissue homeostasis. In tumors, PDGF isoforms are often over-expressed and contribute to the growth of both normal and malignant cells. This review focuses on tumors expressing PDG...