Inhibin is produced by Sertoli cells of the testis, provides negative feedback on FSH secretion, and may prove to be an important marker for the functioning of seminiferous tubules. The purpose of this study was to examine the relationship between the spermatogenic function of the tests of subfertile men and the plasma concentrations of inhibin. The study was carried out on twenty infertile (or...

BACKGROUND This study evaluated hope, depression, anxiety, and stress among three groups of infertile couples. MATERIALS AND METHODS This cross-sectional study consisted of three groups of infertile couples-candidates for oocyte donation (n=60), embryo donation (n=60), and normal infertile (n=60). Participants included couples seen at Royan Institute, Tehran, Iran between 2013-2014 who were a...

OBJECTIVE To illustrate the necessity for an enhanced understanding of the genetic basis of male factor infertility, to present a comprehensive synopsis of these genetic elements, and to review techniques being utilized to produce new insights in fertility research. BACKGROUND Male factor infertility is a complex disorder that affects a large sector of the population; however, many of its eti...

objective: in about 50% of infertile couples a male factor can be found to be present either alone or in addition to other female factors. a new molecular mechanism recently revealed to be involved in infertility is epigenetic pattern modification like as aberrant methylation. this mechanism can change or even silence gene expression. on the other hand, gstm1 (glutathione s-transferase mu 1) ...

Recently, it has been concluded that measurement of the serum free testosterone level is crucial for evaluating male gonadal function. However, the extent of the decline of serum free testosterone levels with aging and the actual levels in male infertility have not yet been clearly defined. In this study, the clinical significance of serum free testosterone levels was evaluated in a total of 24...

It has been documented that almost 50% of the infertility problems are at present attributed to male factors. In IVF centres, potential infertile men are screened for the sperm quality by semen analysis, in particular investigating concentration, motility and morphology according to WHO guidelines [1]. However, at present, these parameters appear to be poor predictors of the fertilization succe...

BACKGROUND Functional male gametes are produced through complex processes that take place within the testis, epididymis and female reproductive tract. A breakdown at any of these phases can result in male infertility. The production of mutant mouse models often yields an unexpected male infertility phenotype. It is with this in mind that the current review has been written. The review aims to a...

INTRODUCTION Although rapid progress has been made in improving fertility in women, the treatment of an infertile male has remained very unsatisfactory. This situation is partly due to paucity of our knowledge regarding the factors controlling spermatogenesis in man. The role of testosterone and gonadotropins in the maintenance of spermatogenesis is not clearly understood (Steinberger, 1971). N...

s The thyroid dysfunction, which is quite prevalent in the population, affects many organs including male and female gonads, thus interfering with the human reproductive physiology. Prolactin has suppressive effect on the pituitary –ovarian axis and may result in amenorrhea or oligomenorrhea due to anovulatory cycles. Hyperprolactinemia is a common problem in reproductive dysfunction, affecting...

Male reproductive health refers to a man’s ability to procreate, and to bring a living being into existence. Male reproductive health has social and psychological impact on normal life (Smith et al., 2009). A normal male reproductive health is a compound result of normal functioning of male reproductive system. In the last 50 years, a significant decrease in human fertility has been observed. I...