The aim of this work was to evaluate the lipid profile Plasmodium berghei infected rats treated with aqueous extract Cassia spectabilis. Twenty five (25) adult male wistar were divided into (5) groups per group. Group I normal control fed only rat chow and water, II parasite without treatment. Groups III IV afterwards 200 mg/kg 400 spectabilis respectively, while V a standard drug (chloroquine)...

this study aimed to observe the protective effects of sufentanil pretreatment on rat cerebral injury during cardiopulmonary bypass (cpb) and to explore the underlying mechanism. twenty-four male adult sprague dawley (sd) rats were divided into 4 groups. then, the rat cpb model was established. a 14g trocar was inserted into the atrium dextrum. for rats in s1 and s5 groups, sufentanil (1 µg•kg-1...

Background: Clinical as well as experimental studies revealed impairment of spermatogenesis in diabetes. Diabetes leads to cell death due to increased oxidative stress. Lepidium sativum (LS) is a plant with antidiabetic effect.The aim of this study was to investigate the protective effect of LS on sperm parameter and testis morphology in adult male rat. Materials and Methods: In this study male...

Resveratrol (3,5,4-trihydroxystilbene) is a natural polyphenolic compound found in grapes and red wine and has been shown to exert protective effects on the liver preventing lipid accumulation induced by a high-fat diet. However, no studies have shown that the nutritional resveratrol intake by the parental generation has modified lipogenesis in an adult offspring. The aim of this study was to i...

The aim of this work was to study age-related changes in the behaviour adult Wistar rats using open field (OF) and elevated plus maze (EPM) tests. Behavioural related motor activity anxiety were particular interest. Results showed that as male female progressed from 2 5 months age, there a decrease level exploratory activities an increase their anxiety. Age-related dependent upon initial indivi...

One of causes in decreasing quantity and quality spermatozoon is disease. Increased blood glucose levels can trigger demage spermatogenesis the testes, thereby reducing spermatozoa production. Biwa leaves (Eriobotrya japonica (Thunb.) Lindl.) contain triterpenes which are expected to overcome cauda epididymis. To investigate this problem, an experimental test nano herbal biwa was carried out a ...

Aim To investigate the anti-inflammatory effect of bezafibrate on acute and subacute inflammation in adult male Wistar rats. Methods The study was carried out rats they were allocated into three groups, that is, control, aspirin bezafibrate, after obtaining clearance from Institutional Animal Ethics Committee. Acute studied using carrageenan-induced rat paw oedema, volume displacement due to oe...

The aim of this study was to evaluate the effect ethanol leaf extract V. amygdalina on testicle alloxan induced diabetic wistar rats. Freshly harvested leaves washed with clean tap water and subsequently dried at room temperature prior being ground fine powder. Twenty (20) adult male rats were divided into four (4) groups five (5) per group. · Group I normal control fed rat chow II diabetes wit...

Background: Ascorbic acid (AA) as a vitamin and neuromodulator is present in the most part of CNS such as nucleus accumbens shell (Acbsh), so the main purpose of this investigation was to evaluated the effect of AA and their Co-administration in Acbsh on anxiety and motor activity of rat by Open Field Test(OFT). Methods: Forty nine adult male Wistar rats (220-270 g) were used into 7 grou...

Objective(s): With no substantial cost, we injected L-arginine into the rat’s corpus callosum (CC) to create animal model of multiple sclerosis (MS) and investigated the pre-injection effect of gold nanoparticles (GNPs). Materials and Methods: Adult male Wistar rat (250-300 g) was surgically cannulated at the CC, and after recovery it was injected L-arginine (3-200 µg/rat, intra-CC) once ...