BACKGROUND Malassezia commensal yeasts along with multitude of antigens have been found to be associated with various skin disorders including Pityriasis versicolor (PV). Amongst them Mala s1, a 37 kDa protein has been proved to be a major allergen reacting with a large panel of sera. However, there exists no therapeutic alternative to combat such problems in form of plant based natural compoun...

Most of the fungal species that infect humans can grow in more than one morphological form but only a subset of pathogens produce filamentous hyphae during the infection process. This subset is phylogenetically unrelated and includes the commonly carried yeasts, Candida albicans, C. dubliniensis, and Malassezia spp., and the acquired pathogens, Aspergillus fumigatus and dermatophytes such as Tr...

BACKGROUND Pityriasis versicolor (PV) is a mild chronic infection of the skin caused by Malassezia yeasts. Although it is primarily seen in adults, children are often affected in the tropics . METHODS Over a period of 2 years, children (up to the age of 14 years) who were clinically and mycologically diagnosed as PV were included in the study. The clinical and epidemiological pattern in diffe...

Atopic dermatitis of the head and neck (HNAD) is recognized as a separate condition. Malassezia, the predominant skin microbiota fungus, is considered to exacerbate atopic dermatitis (AD), especially HNAD. In the present study, we investigated the relationships between the levels of specific IgE antibodies, colonization frequency of eight predominant Malassezia species, and clinical severity in...

Hair samples from 58 healthy camels were examined for the presence of saprophytic fungi. One -hundred and seventy-four samples were obtained from three different locations of dromedary camel's body. Several fungal specific media were used for isolating and identifying the saprophytes. Fungal isolates belonged to 15 genera. The most common in order of frequency were members of the genera Aspergi...

Dermatophyte and yeast species have been screened for their degradative ability towards various keratin substrates. Application of soluble preparation of keratin (KS) of chicken feathers enables a preliminary evaluation of the growth of the fungi and screening of fungal isolates that possesed keratinolytic activity and keratinase enzyme. Five dermatophytes i.e. Trichophyton rubrum, Trichophyton...

Mincle (also called as Clec4e and Clecsf9) is a C-type lectin receptor expressed in activated phagocytes. Recently, we have demonstrated that Mincle is an FcRgamma-associated activating receptor that senses damaged cells. To search an exogenous ligand(s), we screened pathogenic fungi using cell line expressing Mincle, FcRgamma, and NFAT-GFP reporter. We found that Mincle specifically recognizes...

background: malassezia furfur is alipophilic yeast that causes skin disease. objective: to evaluate the level of il-10, ifn-γ and il-12p70 in co-incubation of m. furfur grown on different forms of natural oils with pbmcs of healthy individuals. methods: pbmcs were obtained from blood samples of normal volunteers. m. furfur was cultured in different culture media containing almond oil, fish oil,...

hair samples from 58 healthy camels were examined for the presence of saprophytic fungi. one -hundred and seventy-four samples were obtained from three different locations of dromedary camel's body. several fungal specific media were used for isolating and identifying the saprophytes. fungal isolates belonged to 15 genera. the most common in order of frequency were members of the genera aspergi...