In this paper, a new electromagnetic actuation system is presented for magnetic nano-particles based targeted drug delivery. The system is composed of three sets of coils; each set contains two parallel coils that can generate the oriented 3D magnetic gradient field. Differential Current Coil approach is used to calculate the applied current to each coil to ensure that the gradient field, gener...

We present the synthesis of nonspherical magnetic microparticles with multiple functionalities, shapes, and chemistries. Particle synthesis was performed in two steps: polymeric microparticles functionalized homogenously with carboxyl groups were generated using stop-flow lithography, and then in situ coprecipitation was used to grow magnetic nanoparticles at these carboxyl sites. With successi...

We report on the synthesis and characterization of functional silica hybrid magnetic nanoparticles (SHMNPs). The co-condensation of 3-aminopropyltriethoxysilane (APTES) and tetraethyl orthosilicate (TEOS) in presence of superparamagnetic iron oxide nanoparticles (SPIONs) leads to hybrid magnetic silica particles that are surface-functionalized with primary amino groups. In this work, a comprehe...

Magnetic CoFe2O4 nanoparticles were synthesized via a simple chemical reaction using precipitation method. The obtained materials consist of ferrite particles with average diameter of 25 nm. The effect of different surfactants such as cationic, anionic and neutral on the morphology of the products was investigated. Scanning electron microscopy was used to study the structure and particle size o...

We report a technique to realize reconfigurable colloidal crystals by using the controlled motion of particle defects above an externally modulated magnetic substrate. The transport of particles is induced by applying a uniform rotating magnetic field to a ferrite garnet film characterized by a periodic lattice of magnetic bubbles. For filling factor larger than one colloid per bubble domain, t...

Magnetic particles are used for medical and pharmaceutical purposes such as delivery systems for drugs, genes, and radionuclides. In this study, the technique of chemical co-precipitation in aqueous solution was applied for the synthesis of iron-based magnetic particles. The size and size distribution of magnetic particles were determined by photon correlation spectroscopy. Oxygen-free conditio...

Magnetic particles of iron oxide have been increasingly used in medical diagnosis by magnetic resonance imaging and in cancer therapies involving targeted drug delivery and magnetic hyperthermia. In this study we report the preparation and characterization of iron oxide particles coated with bioceramic hydroxyapatite by spray-drying. The iron oxide magnetic particles (IOMP) were coated with hyd...

The magnetic-force quartz crystal microbalance (QCM) method was attempted for the dynamic evaluation of chemical interactions. Thiol-modified magnetic particles bound to a QCM gold electrode of less than three layers were pulled by a magnetic force, and the dissociation dynamics of the magnetic particles was measured based on the change in the weight as a function of time under different tempe...

We present a microfluidic-based method allowing for the controlled production of lipid particles with encapsulated magnetic nanoparticles (MNPs). Within the same device, the magnetic properties of the composite particles are tested as they flow downstream. The effect of the fluid properties and flow parameters on the size of the microparticles containing MNPs is studied using standard flow visu...