PURPOSE To assess if 3T MRI can be further improved by adding surface coil imaging, in the context of detection and characterization of cerebral lesions in patients with drug-resistant epilepsy. METHODS Twenty five patients with drug-resistant epilepsy undergoing evaluation for epilepsy surgery were examined with high resolution 3T MRI. The patients were MRI-negative (n = 15), or had unclear ...

Branched or multiply branched iron oxide nanoparticles are synthesized, the crystal domains rearrange forming single crystalline structures, that is crucial for efficient magnetic hyperthermia.

Over the past decade, transition metal-based ferrite nanostructures, displaying MFe2O4 stoichiometry (M2+ cations, e.g., Mn, Co, Ni and Zn), have been devised examined primarily owing to their promising applications in cancer nanomedicine. Among these multi-functional spinel ferrites, manganese (MnFe2O4) deserves special attention because it unveils exciting magnetic properties, high chemical s...

The controlled design of robust, well reproducible, and functional nanomaterials made according to simple processes is key importance envision future applications. In the field porous materials, tuning nanoparticle features such as specific area, pore size morphology by adjusting parameters pH, temperature or solvent highly needed. this work, we address tunable control mesoporous silica (MS) na...

The Fe3O4@mSiO2 nanocarrier that consisted of a magnetic Fe3O4 nanoparticle core and a mesoporous silica (mSiO2) shell was synthesized. It shows a uniform sphere morphology about 65 nm in diameter. Considering the magnetic hyperthermia of Fe3O4 under an alternating magnetic field (AMF), a thermo-sensitive polymer, poly[(ethylene glycol)-co-(L-lactide)] (P(EO-co-LLA)), was used as "gatekeeper" c...

The proteasome inhibitor bortezomib (BZ) has shown promising results in some types of cancer, but in others it has had minimal activity. Recent studies have reported enhanced efficacy of BZ when combined with hyperthermia. However, the use of magnetic nanoparticles to induce hyperthermia in combination with BZ has not been reported. This novel hyperthermia modality has shown better potentiation...

Magnetic iron oxide nanoparticles (IONPs) are one of the most extensively studied materials for theranostic applications. IONPs can be used magnetic resonance imaging (MRI), delivery therapeutics, and hyperthermia treatment. Silk is a biocompatible material biomedical Previously, we produced spheres made H2.1MS1 bioengineered silk that specifically carried drug to Her2-overexpressing cancer cel...

This chapter discusses applications of magnetic materials in bioengineering and medicine [1–8]. Magnetism and magnetic materials have been used for many decades in many modern medical applications, and several new applications are being developed in part because of the availability of superior electromagnets, superconducting magnets and permanent magnets [9–12]. Advances in the synthesis and ch...

Introduction:  Image  distortion  is  one  of  the  major  problems  of  magnetic  resonance  imaging  (MRI) for use in 3DMRI, velocity MRI, FMRI and radiotherapy treatment planning (RTTP). It is  widely known that the most obvious effect of the inhomogenity of the magnetic fields and the  nonlinearity  of  the  gradient  is  the  Geometric  Distortion  of  MR  tomograms.  In  this  study,  the...

background and objective: in magnetic fluid hyperthermia therapy, controlling temperature elevation and optimizing heat generation is an immense challenge in practice. the resultant heating configuration by magnetic fluid in the tumor is closely related to the dispersion of particles, frequency and intensity of magnetic field, and biological tissue properties. methods: in this study, to solve h...