conclusions results showed that hcvcp + bcg induced a moderate ctl and mixed th1/th2 immune responses with higher levels of cell proliferation and ifn-γ secretion, indicating that bcg may have a better outcome when formulated in hcvcp-based subunit vaccines. results expression and purification of core protein around the expected size (21 kda) was confirmed by western blotting. the hcvcp + bcg v...

C57BL/10 mice were injected with semiallogeneic (B10.D2 X C57BL/10)F(1) spleen cells via the anterior facial vein within 24 h of birth to induce tolerance to B10.D2 (H-2(d)) alloantigens. Spleen cells from these mice as adults developed reduced, but significant, mixed lymphocyte and cytotoxic lymphocyte responses in vitro to H-2(d) stimulator cells and these treated mice rejected first-set B10....

Background Gag is very important structural protein of human immunodeficiency virus type 1 (HIV-1) and could be detected in early infection. Specific T lymphocyte immune response was regarded as essential in controlling the production and infection. HIV-1 subtype B/C epidemic is speeding in China but limited data is available on the T cell responses covering Gag in the HIV-1 subtype B/C infecto...

experimental autoimmune vitiligo was induced by the intradermal injection of the purified mushroom tyrosinase emulsified in complete freund’s adjuvant (cfa) in female c57bl/6 mice. the onset of vitiligo was characterized by hair hypopigmentation and total melanocyte depletion in the basal layer of the epidermis. oral administration of semipurified mushroom tyrosinase prevented experimental auto...

PURPOSE To study the immunological effects of two types of anesthesia on the immune response in infants during a minimally stressful surgical procedure. METHODS The effects of inhalational halothane (halothane + N2O + O2, spontaneous breathing, n = 12) and conventional balanced anesthesia (thiopental + N2O + O2 + fentanyl + vecuronium, mechanical ventilation, n = 12) on immune function were m...

BACKGROUND Human adenovirus (HAdV) infections are increasingly frequent complications of allogeneic stem-cell transplantation (SCT), especially in children. Only a few data on the correlation between immune recovery and the course of HAdV infection are available, and data on HAdV-specific responses are lacking. METHODS In a prospective study, we determined the correlation between the HAdV DNA...

Many patients attribute their health problems to amalgam and other dental metals. In genetically susceptible indviduals, mercury and gold may function as haptens and elicit allergic and autoimmune reactions. The frequency of metal-induced lymphocyte responses was examined in 3,162 patients in three European laboratories using MELISA(R), an optimized lymphocyte proliferation test. The patients s...