We studied 23 patients suffering cerebral ischemia who also had laboratory evidence of either a lupus anticoagulant (LA) or an abnormal anticardiolipin antibody (ACA). Four patients had lupus or a lupus-like illness, three had drug-induced lupus, and 16 had no overt evidence of collagen-vascular disease. Cerebral ischemic events were multiple in 71% of the patients; two patients presented with ...

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. http://dx.doi.org/10.5045/kjh.2012.47.1.83 The Korean Journal of Hematology Volume 47ᆞNumber...

This issue of Clinical Chemistry and Laboratory Medicine includes a report by Pradella and colleagues regarding a cooperative multicentre study to define the upper limits of normal for several tests used in the diagnostic assessment of lupus anticoagulant (LA) [1] . In total, 200 normal samples were assessed, comprising 40 from each of five centres, for a total of six functional LA assays. Each...

Acute renal infarction is still an underdiagnosed pathology. Most cases are secondary to arterial embolism in patients with atrial fibrillation or other cardiac illnesses; however, a less known etiology is the vascular affection of systemic lupus erythematosus (SLE). Renal infarction in lupus patients normally appears with positive antiphospholipid antibodies or lupus anticoagulant in the conte...