thymoma is a term that should be restricted to neoplasms of thymic epithelial cells, irrespective of the presence or the number of lymphocytes. the usual location of thymoma is the antrosuperior mediastinum; however, this tumor can also occur in other mediastinal compartments, in the neck, within the thyroid gland, in the pericardial cavity, the pulmonary hilum, within the lung parenchyma, or t...

Metastatic neoplasms to the ovary often cause diagnostic problems, in particular those large ovarian masses mimicking primary tumors. Most of these tumors arise from digestive system or breast, while 37-year-old woman diagnosed as right adnexal complex mass, with a subpleural nodule in the apical part of the left lower lobe, at preoperative chest computed tomography scan. The patient underwent ...

The authors describe the incidence of new primary cancers among 4,639 cases of squamous cell skin cancer (SCC) diagnosed between 1974 and 1994 in the cancer registries of the Swiss cantons of Vaud and Neuchâtel (total person-years at risk = 23,152). Overall, 729 metachronous cancers were observed versus 527.6 expected, corresponding to a standardized incidence ratio (SIR) of 1.4 (95% confidence...

From the Section of Interventional Oncology, Department of Radiology (S.C.R.), University of California San Diego Medical Center, San Diego, California; Department of Diagnostic Imaging (D.E.D.), Brown Medical School, Rhode Island Hospital, Providence, Rhode Island; Gastrointestinal/Genitourinary Division, Department of Radiology (D.A.G.), Massachusetts General Hospital, Boston, Massachusetts; ...

We present a clinical case of patient with metachronous primary multiple carcinoma left kidney (2004) adrenal metastasis (2021), occult low-grade follicular thyroid lateral neck lymph node (2019), central lung cancer (2020), hyperparathyroidism coherent parathyroid adenomas intrathyroid and typical location. Patient had undergone left-side nephrectomy bilateral adrenalectomy, double-staged thyr...

CONTEXT MEN1 gene alterations have been implicated in lung carcinoids, but their effect on gene expression and disease outcome is unknown. OBJECTIVE Our objective was to analyze MEN1 gene and expression anomalies in lung neuroendocrine neoplasms and their correlations with clinicopathologic data and disease outcome. DESIGN We examined 74 lung neuroendocrine neoplasms including 58 carcinoids...

With the report of the production of ACTH by non-endocrine neoplastic tissue, Meador and associates set the stage for increasing clinical awareness of ectopic hormone production from a variety of neoplasms, bronchial adenomas and oat cell carcinoma of the lung in particular. The clinical syndromes are those expected from excess secretion of ACTH, ADH, parathyroid hormone, growth hormone, insuli...